IPAC2014 - List of Keywords (cyclotron)

Paper	Title	Other Keywords	Page
MOPME023	A High Precision Particle-moving Algorithm for Particle-in-cell Simulation of Plasma	electron, simulation, plasma, experiment	427
	X.F. Li, D.Z. Chen, D. Li, H.K. Yue HUST, Wuhan, People's Republic of China
	A new particle-moving algorithm for particle-in-cell simulation of plasma is developed based on the Linear Multistep Method. The conventional and the new algorithms are investigated by numerical experiments, which are conducted in three typical fashions of the electron motions in electromagnetic fields, that is, cyclotron in homogeneous magnetic field, drift in field and motions in inhomogeneous magnetic field. The new algorithm not only improves the accuracy but also relaxes the time step condition for the simulation. It can increase the computation efficiency.
DOI •	reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2014-MOPME023
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MOPME029	Simulation of Low Energy Charged Particle Beams	simulation, electron, extraction, quadrupole	442
	O. Karamyshev, C.P. Welsch Cockcroft Institute, Warrington, Cheshire, United Kingdom O. Karamyshev, C.P. Welsch The University of Liverpool, Liverpool, United Kingdom
	Low energy particle beams pose specific challenges to simulation codes and experiments alike as a number of effects become important that can often be neglected at higher beam energies, including e.g. space-charge or fringe field effects. The optimization of low energy charged particle beam transport through arbitrary electromagnetic fields is the purpose of a code aimed at tracking low-energy particles from the sub-eV to the MeV energy range with high precision. The code is based on Matlab/Simulink and able to use 3-dimensional field maps from either Finite Elements Method (FEM) solvers, such as Comsol, OPERA 3D or CST particle studio, fields calculated by the code itself, or field maps from measurements. This contribution describes the code structure and presents its performance limitations. It also gives a summary of results obtained from beam dynamics simulations of cyclotrons injection systems, storage ring extraction systems, electrostatic and magnetic beamlines, as well as from photocathode optimization studies.
DOI •	reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2014-MOPME029
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MOPRI076	Simulation of Dynamics in Ultra-compact Isochronous Medium Energy Racetrack FFAGs	focusing, dynamic-aperture, acceleration, lattice	780
	R. Appleby, J.M. Garland, H.L. Owen, S.C. Tygier UMAN, Manchester, United Kingdom K.M. Hock Cockcroft Institute, Warrington, Cheshire, United Kingdom C. Johnstone PAC, Batavia, Illinois, USA
	Funding: Research supported by STFC grant number ST/K002503/1 "Racetrack FFAGs for medical, PRISM and energy applications". The FFAG (Fixed-Field Alternating-gradient) accelerator is a class of accelerators that comprises the best features of the cyclotron and the synchrotron, combining fixed magnetic fields with strong focusing gradients for optimal stable, low-loss operation. Here, a new type of medium-energy 1-GeV isochronous (CW) FFAG has been developed in a racetrack layout that supports two opposing synchrotron-like straights, permitting both high-gradient RF modules and efficient injection and extraction in a highly compact footprint. In this paper we present beam dynamic simulations for this compact racetrack FFAG, and compare the differences between an equivalent circular and a racetrack configuration. A comparison of the FFAG dynamics with the 800-MeV (Daeδalus) cyclotron is briefly presented.
DOI •	reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2014-MOPRI076
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MOPRI078	High Power Cyclotrons for Neutrino Experiments	experiment, extraction, proton, vacuum	788
	D. Winklehner, J.R. Alonso, W.A. Barletta, A. Calanna, J.M. Conrad MIT, Cambridge, Massachusetts, USA A. Adelmann PSI, Villigen PSI, Switzerland L. Calabretta, D. Campo INFN/LNS, Catania, Italy M. Shaevitz Columbia University, New York, USA J.J. Yang CIAE, Beijing, People's Republic of China
	DAEδALUS* and IsoDAR** experiments needs large intense neutrino fluxes to investigate respectively the CP-Violation in the neutrino sector and the existence of sterile neutrino. DAEδALUS requires three neutrino sources driven by proton beams of ~800 MeV at powers of several megawatts placed at distances of 1.5, 8 and 20 km from the detector. Two cyclotrons working in cascade are chosen to deliver these high power beams. The first cyclotron accelerates the H²⁺ ions beam up to 60 MeV/amu. The beam is then extracted with an electrostatic deflector and reaccelerated up to 800 MeV/amu through a superconducting ring cyclotron. The acceleration of H²⁺ has two advantages: it reduces the space charge effect along the injection and acceleration inside the first cyclotron and allows the extraction of the beam from the last accelerator using a stripper foil. The injector cyclotron can be used in stand-alone mode to drive the IsoDAR experiment, which needs the accelerator placed near an underground neutrino detector. The design and the results of beam dynamic simulations will be shown. the results of preliminary injection and acceleration tests into a cyclotron test bench will be presented. * J. Alonso et al., arXiv:1006.0260[physics.ins-det] (2010). ** A. Bungau et al., Phys. Rev. Lett. 109 141802 (2012).
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MOPRI079	Status of SPES Facility for Acceleration of High Intensity Protons and Production of Exotic Beams	target, proton, neutron, ISOL	791
	M.M. Maggiore, A. Andrighetto, M. Calderolla, J. Esposito, P. Favaron, A. Lombardi, M. Manzolaro, A. Monetti, G.P. Prete, L. Sarchiapone, D. Zafiropoulos INFN/LNL, Legnaro (PD), Italy
	Since 2010 the SPES project has entered in the construction phase at Laboratori Nazionali di Legnaro (LNL) in Italy. The new high power cyclotron is being assembled and tested by BEST Theratronics company in Canada and the installation at LNL site is scheduled for fall 2014. Such machine is able to deliver two simultaneous proton beams in the energy range of 35-70 MeV and 250-500 uA of current and the facility has been designed in order to operate at the same time two different experimental areas. The three main uses of the high power beams are: production of radioactive beams by ISOL technique, production of radioisotopes for research purpose and high intensity neutron beams generation. The configuration of the facility and the further capabilities as multipurpose experimental laboratory will be presented.
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MOPRI080	Measurement of Beam Phase using Phase Probe at the NIRS-930 Cyclotron	acceleration, pick-up, extraction, septum	794
	S. Hojo, K. Katagiri, M. Nakao, A. Noda, K. Noda, A. Sugiura NIRS, Chiba-shi, Japan T. Honma, A.K. Komiyama, T. Okada, Y. Takahashi AEC, Chiba, Japan
	The NIRS-930 cyclotron of the National Institute of Radiological Sciences (NIRS) has been used for production of short-lived radio-pharmaceuticals for PET, research of physics, developments of particle detectors in space, and so on. The NIRS-930 has twelve trim coils for generation of the isochronous fields. Until recently, currents of the twelve trim coils had been adjusted only by monitoring the beam intensity. In order to exactly produce the isochronous fields, a phase probe has been installed in the NIRS-930. Recent results of beam tests using the phase probe will be presented in the present work.
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MOPRI081	Beam Simulation for Improved Operation of Cyclotron NIRS-930	simulation, injection, experiment, extraction	797
	M. Nakao, S. Hojo, K. Katagiri, A. Noda, K. Noda, A. Sugiura NIRS, Chiba-shi, Japan A. Goto Yamagata University, Yamagata, Japan T. Honma, A.K. Komiyama, T. Okada, Y. Takahashi AEC, Chiba, Japan V.L. Smirnov, S.B. Vorozhtsov JINR, Dubna, Moscow Region, Russia
	Beam simulation using SNOP* code has been performed for the cyclotron NIRS-930 at NIRS in order to study beam dynamics in a cyclotron and to improve beam intensity. Each electric or magnetic field (main coil, trim coils, harmonic coils, magnetic channel, gradient corrector, grazer lens, dee electrode, inflector) were calculated by OPERA-3d, and simulated injection, acceleration, and extraction. The simulation of proton with 30 MeV extracting energy with harmonic 1 was already performed and well simulated RF phase and extraction efficiency*. Then we tried to apply SNOP to 18 MeV protons with harmonic 2. We first formed isochronous magnetic field with main and trim coils for simulating single particle. Next we optimized electric deflector and magnetic channel in order to maximize extracted particles simulating the bunch of particles. Beam loss of the simulation was compared to the experiment. And then we are optimizing position and rotation of inflector and position of puller to improve injection. We intend to apply optimized simulation parameter to actual cyclotron operation to improve beam intensity and quality. V.L. Smirnov, S.B. Vorozhtsov, Proc. of RUPAC2012 TUPPB008 325 (2012) ** V.L. Smirnov et al., Proc. of IPAC2012 292 (2012)
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MOPRI082	Acceleration of High-Intensity Heavy-Ion Beams at RIKEN RI Beam Factory	ion, ion-source, ECRIS, linac	800
	O. Kamigaito, T. Dantsuka, M. Fujimaki, N. Fukunishi, H. Hasebe, Y. Higurashi, E. Ikezawa, H. Imao, M. Kase, M. Kidera, M. Komiyama, H. Kuboki, K. Kumagai, T. Maie, T. Nakagawa, M. Nakamura, J. Ohnishi, H. Okuno, K. Ozeki, N. Sakamoto, K. Suda, T. Watanabe, Y. Watanabe, K. Yamada, H. Yamasawa RIKEN Nishina Center, Wako, Japan T. Nagatomo RIKEN, Saitama, Japan
	Recent efforts concerning the RIBF accelerators in RIKEN have been directed towards achieving higher beam intensities of very heavy ions such as uranium and xenon. As presented in the last IPAC conference in 2013, the intensities of these ion beams have significantly improved due to the construction of a new injector, RILAC2, which is equipped with a 28-GHz superconducting ECR ion source, the development of a helium gas stripper, and upgrading of the bending power of the fRC. In this light, this paper presents the subsequent upgrade programs carried out in the last couple of years, such as developments of a new air stripper for xenon beams and a micro-oven for metallic ions. The current performance level of the RIBF accelerator complex, as well as a future plan to further increase the beam intensities, are also presented.
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MOPRI083	Improvement of the Beam Transmission in the Central Region of Warsaw U200P Cyclotron	ion, ion-source, injection, ECR	803
	O. Steczkiewicz, P. Gmaj HIL, Warsaw, Poland V. Bekhterev, I.A. Ivanenko JINR, Dubna, Moscow Region, Russia
	To date, Warsaw U200P cyclotron exploited a mirror inflector to route heavy ions extracted from ECR ion source (10 GHz, 11 kV) to the central region of the cyclotron. However, in such configuration very low transmission was reachable after many optimizations. Additionally, the new ECR ion source (14, 5 GHz, 14-24 kV) was installed, which offers energies far exceeding capabilities of the currently operated inflector and central region. To overcome these obstacles, we have developed a spiral inflector and redesigned central region of the cyclotron. It was a very challenging task, bearing in mind limited volume of central region in our compact machine, to carve these elements suitably for decent versatility of ion beams offered by Warsaw cyclotron. This project was executed in the collaboration with FLNR in Dubna, Russia. The cyclotron equipped with the new central region works in the "constant orbit" regime. Hereby we present the results of both computational simulations and measurements of the beam transmission in upgraded central region.
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MOPRI114	Numerical Estimation of the Equivalent Dose Rate after the Irradiation of a Tungsten Collimator by a Low Energy Proton Beam	proton, simulation, radiation, operation	890
	V. Talanov, D.C. Kiselev, M. Wohlmuther PSI, Villigen PSI, Switzerland
	The issue of activation of a Tungsten collimator by protons is considered for the incident energy of 12.2 MeV. Two different simulation approaches using the Monte Carlo programs MCNPX and FLUKA are applied to estimate the equivalent remanent dose rate after the irradiation of the collimator. The results of the numerical simulation are then compared to the measured dose levels of the collimator of the COMET cyclotron at Paul Scherrer Institut (PSI).
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TUYB01	Vertical Orbit-excursion Fixed Field Alternating Gradient Accelerators (V-FFAGs) and 3D Cyclotrons	closed-orbit, quadrupole, proton, acceleration	956
	S.J. Brooks BNL, Upton, Long Island, New York, USA
	FFAGs with vertical orbit excursion (VFFAGs) provide a promising alternative design for rings with fixed-field (e.g. superconducting) magnets. They have a vertical magnetic field component that increases with height in the vertical aperture, yielding a skew quadrupole focussing structure. Scaling type VFFAGs have fixed tunes and no intrinsic limitation on momentum range; they are also isochronous in the ultra-relativistic limit. Extending isochronism to lower velocities requires a slanted orbit excursion: a three-dimensional analogue of a spiral sector cyclotron from 40 to 1500MeV is developed, which is flat at low energies and acquires a slope as the protons become relativistic. This provides more stable tunes than a comparable planar cyclotron. Such machines are promising future candidates for nuclear transmutation using high average power CW beams at ~GeV energies.
	Slides TUYB01 [16.187 MB]
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TUPRO099	Development of a Method for Measuring the Radial Component of the Magnetic Field in AVF Cyclotrons	experiment, simulation, proton, extraction	1274
	N.A. Morozov, G.A. Karamysheva, S.A. Kostromin, E. Samsonov, N.G. Shakun, E. Syresin JINR, Dubna, Moscow Region, Russia
	In AVF cyclotrons the median plane of the magnetic field rather often does not coincide with the mid-plane of their magnetic system. To measure the radial component of the magnetic field, equipment based on search coils is developed and used to correct the median plane of the magnetic field. The equipment for Br mapping is described. The Br mapping and shimming results are presented for two proton therapy IBA C230 cyclotrons.
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TUPRI031	A Precise Beam Dynamics Model of the PSI Injector 2 to Estimate the Intensity Limit	space-charge, simulation, extraction, acceleration	1630
	A.M. Kolano, R.J. Barlow University of Huddersfield, Huddersfield, United Kingdom A. Adelmann, C. Baumgarten PSI, Villigen PSI, Switzerland
	We describe a precise beam dynamics model of the production set up of the Injector 2 Cyclotron at the Paul Scherrer Institut (PSI). Injector 2 is a 72 MeV separate-sector cyclotron producing a high intensity proton beam up to 2.7 mA CW, which is then injected into the 590 MeV Ring Cyclotron. The model includes space charge and is calculated for optimised matched initial conditions. It has been verified with measurements. Based on this model we estimate the limits to the intensity obtainable from Injector 2. The precise beam dynamics model is based on the OPAL (Object Oriented Parallel Accelerator Library) simulation code, a tool for charged-particle optics calculations in large accelerator structures and beam lines including 3D space charge.
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WEIB01	Global Industrial Development of Accelerators for Charged Particle Therapy	proton, hadron, operation, hadrontherapy	1912
	M. Schillo VMS-PT, Bergisch Gladbach, Germany
	This paper describes the current situation concerning industrial accelerators for medical hadron therapy facilities. Starting from high level requirements and considerations for a therapy facility more specific requirements for the accelerator will be deduced. The Varian ProBeam cyclotron is shown as an example of a medical accelerator and a statistical overview on other accelerators in us is given. The focus is strictly on industrially available equipment. As hadron facilities are extremely complex systems, in the confined space of this paper some simplifications are unavoidable.
	Slides WEIB01 [4.218 MB]
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WEPRO082	A Multi-leaf Faraday Cup Especially for the Therapy of Ocular Tumors with Protons	proton, radiation, ion, extraction	2149
	C.S.G. Kunert, J. Bundesmann, T. Damerow, A. Denker HZB, Berlin, Germany A. Weber Charite, Berlin, Germany
	Funding: Work supported by German Bundesministerium für Bildung und Forschung and Land Berlin The Helmholtz-Zentrum Berlin (HZB) and the University Hospital Charité in Berlin provide a treatment of ocular tumors with a proton beam. The 68 MeV proton beam is delivered by the isochronous HZB-cyclotron as main accelerator. Very important in tumor irradiation treatments is the positioning of the radiation field. For the treatment of eye tumors it is even more important, due to the small and sensitive structures in the eye. Therefore, because of the well-defined Bragg peak, a proton beam is a good choice to achieve very constrained fields of dose delivery. Especially the knowledge of the proton beam energy and the proton beam range with a high accuracy is crucial, due to the small critical structures in the eye. A possible solution for a quick and precise measurement of the range of such proton beams is a Multi-Leaf Faraday Cup (MLFC). This work has the task to develop such a MLFC adapted to the special requirements of the eye tumor therapy. An overview of the progress of this work regarding the MLFC principles and issues such as the first technical realization and results will be given.
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WEPRO088	Design of Beam Transport Lines for Radioisotope Production Systems in NIRS Cyclotron Facility	target, beam-transport, proton, emittance	2162
	K. Katagiri, S. Hojo, M. Nakao, A. Noda, K. Noda, A. Sugiura, K. Suzuki NIRS, Chiba-shi, Japan
	A new beam transport and a irradiation system were designed for radionuclides production with heat damageable targets. The incident beam is swept along a circle on the irradiation target with fast steering magnets. The width and the sweeping radius of the incident beams were optimized to achieve high production efficiency and avoid the heat damages. Based on those optimized parameters, beam optics of the new beam transport lines was optimized. To obtain initial conditions for the optical calculations, the beam emittance and the Twiss parameters were measured at the upper stream of the new beam transport lines. In this paper, we present the results of the calculations and the optimized beam transport lines.
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WEPRO091	Development of Acceleration Technique for Hadron Therapy in JINR	ion, extraction, proton, synchrotron	2171
	E. Syresin JINR, Dubna, Moscow Region, Russia
	Development of accelerators for hadron therapy is one of JINR activities in the field of acceleration technique. The JINR-IBA collaboration has developed and constructed the C235-V3 cyclotron for Dimitrovgrad hospital center of the proton therapy. Proton transmission in C235-V3 from radius 0.3m to 1.03 m is 72% without beam cutting diaphragms, the extraction efficiency is 62%. The cyclotron was delivered in this center in 2012. The project of the medical carbon synchrotron together with superconducting gantry was developed in JINR. Carbon ion beams are effectively used for cancer treatment. The PET is the most effective way of tumor diagnostics. The radioactive carbon ion beam could allow both these advantages to be combined. JINR-NIRS collaboration develops formation of a primary radioactive ion beam for the scanning radiation and on line PET diagnostic. A superconducting cyclotron C400 was designed by the IBA-JINR collaboration. This cyclotron will be used for therapy with proton, helium and carbon ions.
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WEPRO099	A Study of the Production of Neutrons for Boron Neutron Capture Therapy using a Proton Accelerator	neutron, target, proton, ion	2195
	T.R. Edgecock University of Huddersfield, Huddersfield, United Kingdom J.R.J. Bennett STFC/RAL/ISIS, Chilton, Didcot, Oxon, United Kingdom S. Green University Birmingham, Birmingham, United Kingdom B. Phoenix, M.C. Scott Birmingham University, Birmingham, United Kingdom
	Boron Neutron Capture Therapy (BNCT) is a binary cancer therapy particularly well-suited to treating aggressive tumours that exhibit a high degree of infiltration of the surrounding healthy tissue. Such tumours, for example of the brain and lung, provide some of the most challenging problems in oncology. The first element of the therapy is boron-10 which is preferentially introduced into the cancerous cells using a carrier compound. Boron-10 has a very high capture cross-section with the other element of the therapy, thermal neutrons, resulting in the production of a lithium nucleus and an alpha particle which destroy the cell they are created in. However, a large flux of neutrons is required and until recently the only source used was a nuclear reactor. In Birmingham, studies of an existing BNCT facility using a 2.8 MeV proton beam and a solid lithium target have found a way to increase the beam power to a sufficient level to allow clinical trials, while maintaining the target solid. In this paper, we will introduce BNCT, describe the work in Birmingham and compare with other accelerator-driven BNCT projects around the World.
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WEPRO106	Complex “ALFA” After 10 Years of Operation on Track Membranes Production	ion, extraction, injection, ion-source	2212
	G.A. Karamysheva, Yu.N. Denisov JINR, Dubna, Moscow Region, Russia
	The film irradiation complex “ALFA” dedicated to expose the polymer films used in the track membranes production was designed and manufactured by Joint Institute for Nuclear Research for “TRACKPORE TECHNOLOGY" holding company and put into operation in 2002 year in Dubna, Russia. The complex consists of the isochronous cyclotron CYTRACK with external injection of ions, the extraction system, the beam transport of accelerated ions and the film irradiation chamber. Cyclotron CYTRACK accelerates argon ions upto the energy - 2,4 МeV/nucleon, intensity of extracted beam is about 500nA, extraction efficiency totaled 50%. The complex “ALFA” products polyethylene terephthalate track membranes with less than 25 μm thickness and less than 40cm width. After ten years of the successful operation complex “ALFA” was upgraded. Vacuum, control and power supply systems were replaced. As a result the stability and efficiency of the operation of the equipment were increased.
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WEPME008	72 MHz Solid-state Amplifier Power Test	operation, cavity, controls, impedance	2270
	A.Yu. Smirnov, E.V. Ivanov, A.A. Krasnov, S.A. Polikhov, I. Řežanov Siemens Research Center, Moscow,, Russia G.B. Sharkov Siemens LLC, Moscow, Russia
	In this paper, we present the performance of 72 MHz 18 kW RF power source developed for cyclotrons. The machine is equipped with 9 class-AB power amplifier modules (each with up to 2 kW output) based on highly reliable LDMOS transistors. The whole system is arranged inside a single 19" cabinet and has coaxial 50 Ω output. The test environment and high power measurement results are described.
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WEPRI090	Cyclotron C235-V3 for Dimitrovgrad Hospital Center of the Proton Therapy	proton, extraction, acceleration, focusing	2703
	S.A. Kostromin, S. Gurskiy, G.A. Karamysheva, M.Y. Kazarinov, S.A. Korovkin, S.P. Mokrenko, N.A. Morozov, A.G. Olshevsky, V.M. Romanov, E. Samsonov, N.G. Shakun, G. Shirkov, S.G. Shirkov, E. Syresin JINR, Dubna, Moscow Region, Russia P. Cahay, Y. Jongen, Y. Paradis IBA, Louvain-la-Neuve, Belgium
	JINR-IBA C235-V3 isochronous cyclotron for 1st Russian hospital center of the proton therapy has been assembled and tested. Shimming of the magnetic field, optimization of the acceleration modes and testing with the extracted proton beam were done in frame of this work. The paper presents experimental results of the beam dynamics in the accelerator. Proton transmission from radius 30cm to 103cm is 72% without beam cutting diaphragms. The extraction efficiency is 62%. This cyclotron is a substantially modified version C235-V3 of the IBA C235 serial cyclotron. C235-V3 has the improved extraction system which was constructed and tested. This system allows raise the extraction efficiency up to 77% from 50% in comparison with serial C235. Special mapping system (for Br-component) of the magnetic field was developed and constructed by JINR for the shimming of the Br-field in the middle plane of the cyclotron. Total efficiency of the machine is 45%. Further improvement of the parameters expected after final tuning of the cyclotron in Dimitrovgrad.
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THXB01	Accelerators for Medical Application: what is so special?	controls, proton, operation, ion	2807
	J.M. Schippers, M. Seidel PSI, Villigen PSI, Switzerland
	The specific requirements of accelerators for radiation therapy will be discussed. The focus will be on accelerator and beam transport design, but also on operational and formal aspects. We will discuss the special requirements to reach a high reliability for patient treatments as well as an accurate delivery of the dose at the correct position in the patient using modern techniques like pencil beam scanning. The requirements of the beam are quite different from those in a nuclear physics laboratory, such as a special matching of the emittance of the accelerated beam, requirements on beam intensity and stability and prevention of activation. The way of operating a medical device requires not only operators, but also the possibility to have a safe machine operation by non accelerator specialists at different operating sites. Size, weight and price are important for a in a hospital based facility. This is encouraging the application of new developments in superconductivity and has stimulated novel accelerator types and beam sharing schemes. Since certification and legal aspects play an important role in a medical device, these topics will also be discussed.
	Slides THXB01 [2.017 MB]
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THOAB02	Options for UK Technetium-99m Production using Accelerators	target, neutron, linac, proton	2815
	H.L. Owen UMAN, Manchester, United Kingdom J.R. Ballinger KCL, London, United Kingdom J. Buscombe Addenbrooke's Hospital, Cambridge, United Kingdom R.J. Clarke STFC/RAL, Chilton, Didcot, Oxon, United Kingdom E. Denton Norfolk and Norwich University Hospital, Norwich, United Kingdom B. Ellis Central Manchester University Hospital, Manchester, United Kingdom G.D. Flux Royal Marsden NHS Foundation Trust, London, United Kingdom L. Fraser PHE, London, United Kingdom B.J. Neilly University of Glasgow, Glasgow, United Kingdom A. Paterson The Society of Radiographers, London, United Kingdom A. Perkins University of Nottingham, Nottingham, United Kingdom A.F. Scarsbrook Leeds Teaching Hospitals NHS Trust, St James's University Hospital, Leeds, United Kingdom
	Recent and ongoing shortages in reactor-based supplies of Molybdenum-99 for hospital production of the important medical radioisotope Technetium-99m have prompted the re-examination of the alternative production methods using conventional and laser-based particle accelerators. At present the UK has no domestic Technetium-99m production and relies exclusively on Technetium-99m generators manufactured overseas; the National Health Service, with professional partners, is therefore examining the options for domestic production to increase security of supply. In this paper we review the accelerator-based methods from a UK perspective, and outline the most promising methods for short- and medium-term supply, which include low-energy cyclotron and photonuclear reaction routes using enriched Molybdenum-100 targets.
	Slides THOAB02 [38.942 MB]
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THPRO070	Beam Dynamics Simulations in Cyclotron C230 Considering Imperfections of Magnetic Field Radial Component	proton, acceleration, simulation, focusing	3038
	E. Samsonov, S.A. Kostromin, N.A. Morozov, E. Syresin JINR, Dubna, Moscow Region, Russia
	Simulations concern to a beam axial motion in the IBA cyclotron C230 that is a base facility in several medical centers worldwide. Because of small axial focusing of the beam in a center of the cyclotron the radial component of magnetic field imperfections leads to additional proton losses. Measured maps of the axial and radial components of magnetic field were used in the simulations. It was found that the radial component with value 5-10 G in the center and approximately 2 G in the main region of acceleration leads to decrease of the resulting beam intensity by about two times and to increase the beam axial width by 25% as well. Simulations define the requirements to the experimental radial component shaping for the next cyclotrons of this series. Providing these requirements will ensure an absence of the additional proton losses due to the axial motion perturbations.
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THPME067	Air Stripper for Intense Heavy Ion Beams	target, ion, heavy-ion, acceleration	3388
	H. Imao RIKEN Nishina Center for Accelerator-Based Science, Wako, Saitama, Japan M. Fujimaki, N. Fukunishi, H. Hasebe, O. Kamigaito, M. Kase, H. Kuboki, H. Okuno, Y. Yano RIKEN Nishina Center, Wako, Japan
	Intensity upgrade of very heavy ions such as uranium or xenon beams is one of the main concerns at the RIKEN Radioactive Isotope Beam Factory (RIBF). The lifetime problem of carbon-foil strippers due to the high energy loss of beams was a principal bottleneck for the intensity upgrade. We have already developed and successfully operated a re-circulating He-gas stripper for 10-MeV/u uranium beams as an alternative to carbon foils. Recently, the 2nd gas stripper with air dedicated for 50-MeV/u ¹²⁴Xe beams was developed. The differential pumping techniques similar to that used in the He gas stripper was applied. We confined a very thick gas target, up to 20~mg/cm² of air, in a 0.5-m target chamber. One good feature of using air is that it can be inexhaustible for our use. The stripper was stably operated in user runs performed in June 2013. The service rate reached 91\%. The maximum beam intensity reached 38~pnA and the average intensity provided to users becomes approximately four times higher than it was in 2012. The down-time free gas strippers greatly contributed to these improvements. We also discuss the applicability of the air stripper to 50-MeV/u ²³⁸U beams.
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THPME195	Nondestructive Beam Current Monitor for the 88-inch Cyclotron	ion, ion-source, operation, heavy-ion	3738
	M. Kireeff Covo LBNL, Berkeley, California, USA
	Funding: This work was supported by the Director, Office of Science, Office of Nuclear Physics, Division of Nuclear Physics, US Department of Energy under Contract No. DE-AC02-05CH11231. A fast current transformer is mounted in the staging line of the Berkeley 88-inch isochronous cyclotron. The measured signal is amplified and connected to the input of a lock-in amplifier. The lock-in amplifier detects the signal vector from the input signal at the RF reference frequency of the cyclotron second harmonic. The magnitude of the signal detected is calibrated against a Faraday cup and shows the beam current leaving the cyclotron.
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THPRI083	Target Design for the ISODAR Neutrino Experiment	neutron, target, proton, shielding	3964
	A. Bungau, R.J. Barlow University of Huddersfield, Huddersfield, United Kingdom J.R. Alonso, L.M. Bartoszek, J.M. Conrad, M. Moulai MIT, Cambridge, Massachusetts, USA M. Shaevitz Columbia University, New York, USA
	This paper focuses on the design of a high-intensity antineutrino source from the production and subsequent decay of Li8. The Geant4 code is used to calculate the anti-neutrino flux that can be obtained along with the production of undesirable contaminants. We present in this paper the optimised design for the target, moderators, reflector and shielding. Engineering issues associated with this design are also discussed in this paper.
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Paper

Title

Other Keywords

Page

MOPME023

A High Precision Particle-moving Algorithm for Particle-in-cell Simulation of Plasma

electron, simulation, plasma, experiment

427

X.F. Li, D.Z. Chen, D. Li, H.K. Yue
HUST, Wuhan, People's Republic of China

A new particle-moving algorithm for particle-in-cell simulation of plasma is developed based on the Linear Multistep Method. The conventional and the new algorithms are investigated by numerical experiments, which are conducted in three typical fashions of the electron motions in electromagnetic fields, that is, cyclotron in homogeneous magnetic field, drift in field and motions in inhomogeneous magnetic field. The new algorithm not only improves the accuracy but also relaxes the time step condition for the simulation. It can increase the computation efficiency.

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MOPME029

Simulation of Low Energy Charged Particle Beams

simulation, electron, extraction, quadrupole

442

O. Karamyshev, C.P. Welsch
Cockcroft Institute, Warrington, Cheshire, United Kingdom
O. Karamyshev, C.P. Welsch
The University of Liverpool, Liverpool, United Kingdom

Low energy particle beams pose specific challenges to simulation codes and experiments alike as a number of effects become important that can often be neglected at higher beam energies, including e.g. space-charge or fringe field effects. The optimization of low energy charged particle beam transport through arbitrary electromagnetic fields is the purpose of a code aimed at tracking low-energy particles from the sub-eV to the MeV energy range with high precision. The code is based on Matlab/Simulink and able to use 3-dimensional field maps from either Finite Elements Method (FEM) solvers, such as Comsol, OPERA 3D or CST particle studio, fields calculated by the code itself, or field maps from measurements. This contribution describes the code structure and presents its performance limitations. It also gives a summary of results obtained from beam dynamics simulations of cyclotrons injection systems, storage ring extraction systems, electrostatic and magnetic beamlines, as well as from photocathode optimization studies.

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MOPRI076

Simulation of Dynamics in Ultra-compact Isochronous Medium Energy Racetrack FFAGs

focusing, dynamic-aperture, acceleration, lattice

780

R. Appleby, J.M. Garland, H.L. Owen, S.C. Tygier
UMAN, Manchester, United Kingdom
K.M. Hock
Cockcroft Institute, Warrington, Cheshire, United Kingdom
C. Johnstone
PAC, Batavia, Illinois, USA

Funding: Research supported by STFC grant number ST/K002503/1 "Racetrack FFAGs for medical, PRISM and energy applications".
The FFAG (Fixed-Field Alternating-gradient) accelerator is a class of accelerators that comprises the best features of the cyclotron and the synchrotron, combining fixed magnetic fields with strong focusing gradients for optimal stable, low-loss operation. Here, a new type of medium-energy 1-GeV isochronous (CW) FFAG has been developed in a racetrack layout that supports two opposing synchrotron-like straights, permitting both high-gradient RF modules and efficient injection and extraction in a highly compact footprint. In this paper we present beam dynamic simulations for this compact racetrack FFAG, and compare the differences between an equivalent circular and a racetrack configuration. A comparison of the FFAG dynamics with the 800-MeV (Daeδalus) cyclotron is briefly presented.

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MOPRI078

High Power Cyclotrons for Neutrino Experiments

experiment, extraction, proton, vacuum

788

D. Winklehner, J.R. Alonso, W.A. Barletta, A. Calanna, J.M. Conrad
MIT, Cambridge, Massachusetts, USA
A. Adelmann
PSI, Villigen PSI, Switzerland
L. Calabretta, D. Campo
INFN/LNS, Catania, Italy
M. Shaevitz
Columbia University, New York, USA
J.J. Yang
CIAE, Beijing, People's Republic of China

DAEδALUS* and IsoDAR** experiments needs large intense neutrino fluxes to investigate respectively the CP-Violation in the neutrino sector and the existence of sterile neutrino. DAEδALUS requires three neutrino sources driven by proton beams of ~800 MeV at powers of several megawatts placed at distances of 1.5, 8 and 20 km from the detector. Two cyclotrons working in cascade are chosen to deliver these high power beams. The first cyclotron accelerates the H²⁺ ions beam up to 60 MeV/amu. The beam is then extracted with an electrostatic deflector and reaccelerated up to 800 MeV/amu through a superconducting ring cyclotron. The acceleration of H²⁺ has two advantages: it reduces the space charge effect along the injection and acceleration inside the first cyclotron and allows the extraction of the beam from the last accelerator using a stripper foil. The injector cyclotron can be used in stand-alone mode to drive the IsoDAR experiment, which needs the accelerator placed near an underground neutrino detector. The design and the results of beam dynamic simulations will be shown. the results of preliminary injection and acceleration tests into a cyclotron test bench will be presented.
* J. Alonso et al., arXiv:1006.0260[physics.ins-det] (2010).
** A. Bungau et al., Phys. Rev. Lett. 109 141802 (2012).

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MOPRI079

Status of SPES Facility for Acceleration of High Intensity Protons and Production of Exotic Beams

target, proton, neutron, ISOL

791

M.M. Maggiore, A. Andrighetto, M. Calderolla, J. Esposito, P. Favaron, A. Lombardi, M. Manzolaro, A. Monetti, G.P. Prete, L. Sarchiapone, D. Zafiropoulos
INFN/LNL, Legnaro (PD), Italy

Since 2010 the SPES project has entered in the construction phase at Laboratori Nazionali di Legnaro (LNL) in Italy. The new high power cyclotron is being assembled and tested by BEST Theratronics company in Canada and the installation at LNL site is scheduled for fall 2014. Such machine is able to deliver two simultaneous proton beams in the energy range of 35-70 MeV and 250-500 uA of current and the facility has been designed in order to operate at the same time two different experimental areas. The three main uses of the high power beams are: production of radioactive beams by ISOL technique, production of radioisotopes for research purpose and high intensity neutron beams generation. The configuration of the facility and the further capabilities as multipurpose experimental laboratory will be presented.

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MOPRI080

Measurement of Beam Phase using Phase Probe at the NIRS-930 Cyclotron

acceleration, pick-up, extraction, septum

794

S. Hojo, K. Katagiri, M. Nakao, A. Noda, K. Noda, A. Sugiura
NIRS, Chiba-shi, Japan
T. Honma, A.K. Komiyama, T. Okada, Y. Takahashi
AEC, Chiba, Japan

The NIRS-930 cyclotron of the National Institute of Radiological Sciences (NIRS) has been used for production of short-lived radio-pharmaceuticals for PET, research of physics, developments of particle detectors in space, and so on. The NIRS-930 has twelve trim coils for generation of the isochronous fields. Until recently, currents of the twelve trim coils had been adjusted only by monitoring the beam intensity. In order to exactly produce the isochronous fields, a phase probe has been installed in the NIRS-930. Recent results of beam tests using the phase probe will be presented in the present work.

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MOPRI081

Beam Simulation for Improved Operation of Cyclotron NIRS-930

simulation, injection, experiment, extraction

797

M. Nakao, S. Hojo, K. Katagiri, A. Noda, K. Noda, A. Sugiura
NIRS, Chiba-shi, Japan
A. Goto
Yamagata University, Yamagata, Japan
T. Honma, A.K. Komiyama, T. Okada, Y. Takahashi
AEC, Chiba, Japan
V.L. Smirnov, S.B. Vorozhtsov
JINR, Dubna, Moscow Region, Russia

Beam simulation using SNOP* code has been performed for the cyclotron NIRS-930 at NIRS in order to study beam dynamics in a cyclotron and to improve beam intensity. Each electric or magnetic field (main coil, trim coils, harmonic coils, magnetic channel, gradient corrector, grazer lens, dee electrode, inflector) were calculated by OPERA-3d, and simulated injection, acceleration, and extraction. The simulation of proton with 30 MeV extracting energy with harmonic 1 was already performed and well simulated RF phase and extraction efficiency**. Then we tried to apply SNOP to 18 MeV protons with harmonic 2. We first formed isochronous magnetic field with main and trim coils for simulating single particle. Next we optimized electric deflector and magnetic channel in order to maximize extracted particles simulating the bunch of particles. Beam loss of the simulation was compared to the experiment. And then we are optimizing position and rotation of inflector and position of puller to improve injection. We intend to apply optimized simulation parameter to actual cyclotron operation to improve beam intensity and quality.
* V.L. Smirnov, S.B. Vorozhtsov, Proc. of RUPAC2012 TUPPB008 325 (2012)
** V.L. Smirnov et al., Proc. of IPAC2012 292 (2012)

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MOPRI082

Acceleration of High-Intensity Heavy-Ion Beams at RIKEN RI Beam Factory

ion, ion-source, ECRIS, linac

800

O. Kamigaito, T. Dantsuka, M. Fujimaki, N. Fukunishi, H. Hasebe, Y. Higurashi, E. Ikezawa, H. Imao, M. Kase, M. Kidera, M. Komiyama, H. Kuboki, K. Kumagai, T. Maie, T. Nakagawa, M. Nakamura, J. Ohnishi, H. Okuno, K. Ozeki, N. Sakamoto, K. Suda, T. Watanabe, Y. Watanabe, K. Yamada, H. Yamasawa
RIKEN Nishina Center, Wako, Japan
T. Nagatomo
RIKEN, Saitama, Japan

Recent efforts concerning the RIBF accelerators in RIKEN have been directed towards achieving higher beam intensities of very heavy ions such as uranium and xenon. As presented in the last IPAC conference in 2013, the intensities of these ion beams have significantly improved due to the construction of a new injector, RILAC2, which is equipped with a 28-GHz superconducting ECR ion source, the development of a helium gas stripper, and upgrading of the bending power of the fRC. In this light, this paper presents the subsequent upgrade programs carried out in the last couple of years, such as developments of a new air stripper for xenon beams and a micro-oven for metallic ions. The current performance level of the RIBF accelerator complex, as well as a future plan to further increase the beam intensities, are also presented.

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MOPRI083

Improvement of the Beam Transmission in the Central Region of Warsaw U200P Cyclotron

ion, ion-source, injection, ECR

803

O. Steczkiewicz, P. Gmaj
HIL, Warsaw, Poland
V. Bekhterev, I.A. Ivanenko
JINR, Dubna, Moscow Region, Russia

To date, Warsaw U200P cyclotron exploited a mirror inflector to route heavy ions extracted from ECR ion source (10 GHz, 11 kV) to the central region of the cyclotron. However, in such configuration very low transmission was reachable after many optimizations. Additionally, the new ECR ion source (14, 5 GHz, 14-24 kV) was installed, which offers energies far exceeding capabilities of the currently operated inflector and central region. To overcome these obstacles, we have developed a spiral inflector and redesigned central region of the cyclotron. It was a very challenging task, bearing in mind limited volume of central region in our compact machine, to carve these elements suitably for decent versatility of ion beams offered by Warsaw cyclotron. This project was executed in the collaboration with FLNR in Dubna, Russia. The cyclotron equipped with the new central region works in the "constant orbit" regime. Hereby we present the results of both computational simulations and measurements of the beam transmission in upgraded central region.

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MOPRI114

Numerical Estimation of the Equivalent Dose Rate after the Irradiation of a Tungsten Collimator by a Low Energy Proton Beam

proton, simulation, radiation, operation

890

V. Talanov, D.C. Kiselev, M. Wohlmuther
PSI, Villigen PSI, Switzerland

The issue of activation of a Tungsten collimator by protons is considered for the incident energy of 12.2 MeV. Two different simulation approaches using the Monte Carlo programs MCNPX and FLUKA are applied to estimate the equivalent remanent dose rate after the irradiation of the collimator. The results of the numerical simulation are then compared to the measured dose levels of the collimator of the COMET cyclotron at Paul Scherrer Institut (PSI).

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TUYB01

Vertical Orbit-excursion Fixed Field Alternating Gradient Accelerators (V-FFAGs) and 3D Cyclotrons

closed-orbit, quadrupole, proton, acceleration

956

S.J. Brooks
BNL, Upton, Long Island, New York, USA

FFAGs with vertical orbit excursion (VFFAGs) provide a promising alternative design for rings with fixed-field (e.g. superconducting) magnets. They have a vertical magnetic field component that increases with height in the vertical aperture, yielding a skew quadrupole focussing structure. Scaling type VFFAGs have fixed tunes and no intrinsic limitation on momentum range; they are also isochronous in the ultra-relativistic limit. Extending isochronism to lower velocities requires a slanted orbit excursion: a three-dimensional analogue of a spiral sector cyclotron from 40 to 1500MeV is developed, which is flat at low energies and acquires a slope as the protons become relativistic. This provides more stable tunes than a comparable planar cyclotron. Such machines are promising future candidates for nuclear transmutation using high average power CW beams at ~GeV energies.

Slides TUYB01 [16.187 MB]

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TUPRO099

Development of a Method for Measuring the Radial Component of the Magnetic Field in AVF Cyclotrons

experiment, simulation, proton, extraction

1274

N.A. Morozov, G.A. Karamysheva, S.A. Kostromin, E. Samsonov, N.G. Shakun, E. Syresin
JINR, Dubna, Moscow Region, Russia

In AVF cyclotrons the median plane of the magnetic field rather often does not coincide with the mid-plane of their magnetic system. To measure the radial component of the magnetic field, equipment based on search coils is developed and used to correct the median plane of the magnetic field. The equipment for Br mapping is described. The Br mapping and shimming results are presented for two proton therapy IBA C230 cyclotrons.

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TUPRI031

A Precise Beam Dynamics Model of the PSI Injector 2 to Estimate the Intensity Limit

space-charge, simulation, extraction, acceleration

1630

A.M. Kolano, R.J. Barlow
University of Huddersfield, Huddersfield, United Kingdom
A. Adelmann, C. Baumgarten
PSI, Villigen PSI, Switzerland

We describe a precise beam dynamics model of the production set up of the Injector 2 Cyclotron at the Paul Scherrer Institut (PSI). Injector 2 is a 72 MeV separate-sector cyclotron producing a high intensity proton beam up to 2.7 mA CW, which is then injected into the 590 MeV Ring Cyclotron. The model includes space charge and is calculated for optimised matched initial conditions. It has been verified with measurements. Based on this model we estimate the limits to the intensity obtainable from Injector 2. The precise beam dynamics model is based on the OPAL (Object Oriented Parallel Accelerator Library) simulation code, a tool for charged-particle optics calculations in large accelerator structures and beam lines including 3D space charge.

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WEIB01

Global Industrial Development of Accelerators for Charged Particle Therapy

proton, hadron, operation, hadrontherapy

1912

M. Schillo
VMS-PT, Bergisch Gladbach, Germany

This paper describes the current situation concerning industrial accelerators for medical hadron therapy facilities. Starting from high level requirements and considerations for a therapy facility more specific requirements for the accelerator will be deduced. The Varian ProBeam cyclotron is shown as an example of a medical accelerator and a statistical overview on other accelerators in us is given. The focus is strictly on industrially available equipment. As hadron facilities are extremely complex systems, in the confined space of this paper some simplifications are unavoidable.

Slides WEIB01 [4.218 MB]

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WEPRO082

A Multi-leaf Faraday Cup Especially for the Therapy of Ocular Tumors with Protons

proton, radiation, ion, extraction

2149

C.S.G. Kunert, J. Bundesmann, T. Damerow, A. Denker
HZB, Berlin, Germany
A. Weber
Charite, Berlin, Germany

Funding: Work supported by German Bundesministerium für Bildung und Forschung and Land Berlin
The Helmholtz-Zentrum Berlin (HZB) and the University Hospital Charité in Berlin provide a treatment of ocular tumors with a proton beam. The 68 MeV proton beam is delivered by the isochronous HZB-cyclotron as main accelerator. Very important in tumor irradiation treatments is the positioning of the radiation field. For the treatment of eye tumors it is even more important, due to the small and sensitive structures in the eye. Therefore, because of the well-defined Bragg peak, a proton beam is a good choice to achieve very constrained fields of dose delivery. Especially the knowledge of the proton beam energy and the proton beam range with a high accuracy is crucial, due to the small critical structures in the eye. A possible solution for a quick and precise measurement of the range of such proton beams is a Multi-Leaf Faraday Cup (MLFC). This work has the task to develop such a MLFC adapted to the special requirements of the eye tumor therapy. An overview of the progress of this work regarding the MLFC principles and issues such as the first technical realization and results will be given.

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WEPRO088

Design of Beam Transport Lines for Radioisotope Production Systems in NIRS Cyclotron Facility

target, beam-transport, proton, emittance

2162

K. Katagiri, S. Hojo, M. Nakao, A. Noda, K. Noda, A. Sugiura, K. Suzuki
NIRS, Chiba-shi, Japan

A new beam transport and a irradiation system were designed for radionuclides production with heat damageable targets. The incident beam is swept along a circle on the irradiation target with fast steering magnets. The width and the sweeping radius of the incident beams were optimized to achieve high production efficiency and avoid the heat damages. Based on those optimized parameters, beam optics of the new beam transport lines was optimized. To obtain initial conditions for the optical calculations, the beam emittance and the Twiss parameters were measured at the upper stream of the new beam transport lines. In this paper, we present the results of the calculations and the optimized beam transport lines.

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WEPRO091

Development of Acceleration Technique for Hadron Therapy in JINR

ion, extraction, proton, synchrotron

2171

E. Syresin
JINR, Dubna, Moscow Region, Russia

Development of accelerators for hadron therapy is one of JINR activities in the field of acceleration technique. The JINR-IBA collaboration has developed and constructed the C235-V3 cyclotron for Dimitrovgrad hospital center of the proton therapy. Proton transmission in C235-V3 from radius 0.3m to 1.03 m is 72% without beam cutting diaphragms, the extraction efficiency is 62%. The cyclotron was delivered in this center in 2012. The project of the medical carbon synchrotron together with superconducting gantry was developed in JINR. Carbon ion beams are effectively used for cancer treatment. The PET is the most effective way of tumor diagnostics. The radioactive carbon ion beam could allow both these advantages to be combined. JINR-NIRS collaboration develops formation of a primary radioactive ion beam for the scanning radiation and on line PET diagnostic. A superconducting cyclotron C400 was designed by the IBA-JINR collaboration. This cyclotron will be used for therapy with proton, helium and carbon ions.

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WEPRO099

A Study of the Production of Neutrons for Boron Neutron Capture Therapy using a Proton Accelerator

neutron, target, proton, ion

2195

T.R. Edgecock
University of Huddersfield, Huddersfield, United Kingdom
J.R.J. Bennett
STFC/RAL/ISIS, Chilton, Didcot, Oxon, United Kingdom
S. Green
University Birmingham, Birmingham, United Kingdom
B. Phoenix, M.C. Scott
Birmingham University, Birmingham, United Kingdom

Boron Neutron Capture Therapy (BNCT) is a binary cancer therapy particularly well-suited to treating aggressive tumours that exhibit a high degree of infiltration of the surrounding healthy tissue. Such tumours, for example of the brain and lung, provide some of the most challenging problems in oncology. The first element of the therapy is boron-10 which is preferentially introduced into the cancerous cells using a carrier compound. Boron-10 has a very high capture cross-section with the other element of the therapy, thermal neutrons, resulting in the production of a lithium nucleus and an alpha particle which destroy the cell they are created in. However, a large flux of neutrons is required and until recently the only source used was a nuclear reactor. In Birmingham, studies of an existing BNCT facility using a 2.8 MeV proton beam and a solid lithium target have found a way to increase the beam power to a sufficient level to allow clinical trials, while maintaining the target solid. In this paper, we will introduce BNCT, describe the work in Birmingham and compare with other accelerator-driven BNCT projects around the World.

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reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2014-WEPRO099

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WEPRO106

Complex “ALFA” After 10 Years of Operation on Track Membranes Production

ion, extraction, injection, ion-source

2212

G.A. Karamysheva, Yu.N. Denisov
JINR, Dubna, Moscow Region, Russia

The film irradiation complex “ALFA” dedicated to expose the polymer films used in the track membranes production was designed and manufactured by Joint Institute for Nuclear Research for “TRACKPORE TECHNOLOGY" holding company and put into operation in 2002 year in Dubna, Russia. The complex consists of the isochronous cyclotron CYTRACK with external injection of ions, the extraction system, the beam transport of accelerated ions and the film irradiation chamber. Cyclotron CYTRACK accelerates argon ions upto the energy - 2,4 МeV/nucleon, intensity of extracted beam is about 500nA, extraction efficiency totaled 50%. The complex “ALFA” products polyethylene terephthalate track membranes with less than 25 μm thickness and less than 40cm width. After ten years of the successful operation complex “ALFA” was upgraded. Vacuum, control and power supply systems were replaced. As a result the stability and efficiency of the operation of the equipment were increased.

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WEPME008

72 MHz Solid-state Amplifier Power Test

operation, cavity, controls, impedance

2270

A.Yu. Smirnov, E.V. Ivanov, A.A. Krasnov, S.A. Polikhov, I. Řežanov
Siemens Research Center, Moscow,, Russia
G.B. Sharkov
Siemens LLC, Moscow, Russia

In this paper, we present the performance of 72 MHz 18 kW RF power source developed for cyclotrons. The machine is equipped with 9 class-AB power amplifier modules (each with up to 2 kW output) based on highly reliable LDMOS transistors. The whole system is arranged inside a single 19" cabinet and has coaxial 50 Ω output. The test environment and high power measurement results are described.

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WEPRI090

Cyclotron C235-V3 for Dimitrovgrad Hospital Center of the Proton Therapy

proton, extraction, acceleration, focusing

2703

S.A. Kostromin, S. Gurskiy, G.A. Karamysheva, M.Y. Kazarinov, S.A. Korovkin, S.P. Mokrenko, N.A. Morozov, A.G. Olshevsky, V.M. Romanov, E. Samsonov, N.G. Shakun, G. Shirkov, S.G. Shirkov, E. Syresin
JINR, Dubna, Moscow Region, Russia
P. Cahay, Y. Jongen, Y. Paradis
IBA, Louvain-la-Neuve, Belgium

JINR-IBA C235-V3 isochronous cyclotron for 1st Russian hospital center of the proton therapy has been assembled and tested. Shimming of the magnetic field, optimization of the acceleration modes and testing with the extracted proton beam were done in frame of this work. The paper presents experimental results of the beam dynamics in the accelerator. Proton transmission from radius 30cm to 103cm is 72% without beam cutting diaphragms. The extraction efficiency is 62%. This cyclotron is a substantially modified version C235-V3 of the IBA C235 serial cyclotron. C235-V3 has the improved extraction system which was constructed and tested. This system allows raise the extraction efficiency up to 77% from 50% in comparison with serial C235. Special mapping system (for Br-component) of the magnetic field was developed and constructed by JINR for the shimming of the Br-field in the middle plane of the cyclotron. Total efficiency of the machine is 45%. Further improvement of the parameters expected after final tuning of the cyclotron in Dimitrovgrad.

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THXB01

Accelerators for Medical Application: what is so special?

controls, proton, operation, ion

2807

J.M. Schippers, M. Seidel
PSI, Villigen PSI, Switzerland

The specific requirements of accelerators for radiation therapy will be discussed. The focus will be on accelerator and beam transport design, but also on operational and formal aspects. We will discuss the special requirements to reach a high reliability for patient treatments as well as an accurate delivery of the dose at the correct position in the patient using modern techniques like pencil beam scanning. The requirements of the beam are quite different from those in a nuclear physics laboratory, such as a special matching of the emittance of the accelerated beam, requirements on beam intensity and stability and prevention of activation. The way of operating a medical device requires not only operators, but also the possibility to have a safe machine operation by non accelerator specialists at different operating sites. Size, weight and price are important for a in a hospital based facility. This is encouraging the application of new developments in superconductivity and has stimulated novel accelerator types and beam sharing schemes. Since certification and legal aspects play an important role in a medical device, these topics will also be discussed.

Slides THXB01 [2.017 MB]

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THOAB02

Options for UK Technetium-99m Production using Accelerators

target, neutron, linac, proton

2815

H.L. Owen
UMAN, Manchester, United Kingdom
J.R. Ballinger
KCL, London, United Kingdom
J. Buscombe
Addenbrooke's Hospital, Cambridge, United Kingdom
R.J. Clarke
STFC/RAL, Chilton, Didcot, Oxon, United Kingdom
E. Denton
Norfolk and Norwich University Hospital, Norwich, United Kingdom
B. Ellis
Central Manchester University Hospital, Manchester, United Kingdom
G.D. Flux
Royal Marsden NHS Foundation Trust, London, United Kingdom
L. Fraser
PHE, London, United Kingdom
B.J. Neilly
University of Glasgow, Glasgow, United Kingdom
A. Paterson
The Society of Radiographers, London, United Kingdom
A. Perkins
University of Nottingham, Nottingham, United Kingdom
A.F. Scarsbrook
Leeds Teaching Hospitals NHS Trust, St James's University Hospital, Leeds, United Kingdom

Recent and ongoing shortages in reactor-based supplies of Molybdenum-99 for hospital production of the important medical radioisotope Technetium-99m have prompted the re-examination of the alternative production methods using conventional and laser-based particle accelerators. At present the UK has no domestic Technetium-99m production and relies exclusively on Technetium-99m generators manufactured overseas; the National Health Service, with professional partners, is therefore examining the options for domestic production to increase security of supply. In this paper we review the accelerator-based methods from a UK perspective, and outline the most promising methods for short- and medium-term supply, which include low-energy cyclotron and photonuclear reaction routes using enriched Molybdenum-100 targets.

Slides THOAB02 [38.942 MB]

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THPRO070

Beam Dynamics Simulations in Cyclotron C230 Considering Imperfections of Magnetic Field Radial Component

proton, acceleration, simulation, focusing

3038

E. Samsonov, S.A. Kostromin, N.A. Morozov, E. Syresin
JINR, Dubna, Moscow Region, Russia

Simulations concern to a beam axial motion in the IBA cyclotron C230 that is a base facility in several medical centers worldwide. Because of small axial focusing of the beam in a center of the cyclotron the radial component of magnetic field imperfections leads to additional proton losses. Measured maps of the axial and radial components of magnetic field were used in the simulations. It was found that the radial component with value 5-10 G in the center and approximately 2 G in the main region of acceleration leads to decrease of the resulting beam intensity by about two times and to increase the beam axial width by 25% as well. Simulations define the requirements to the experimental radial component shaping for the next cyclotrons of this series. Providing these requirements will ensure an absence of the additional proton losses due to the axial motion perturbations.

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THPME067

Air Stripper for Intense Heavy Ion Beams

target, ion, heavy-ion, acceleration

3388

H. Imao
RIKEN Nishina Center for Accelerator-Based Science, Wako, Saitama, Japan
M. Fujimaki, N. Fukunishi, H. Hasebe, O. Kamigaito, M. Kase, H. Kuboki, H. Okuno, Y. Yano
RIKEN Nishina Center, Wako, Japan

Intensity upgrade of very heavy ions such as uranium or xenon beams is one of the main concerns at the RIKEN Radioactive Isotope Beam Factory (RIBF). The lifetime problem of carbon-foil strippers due to the high energy loss of beams was a principal bottleneck for the intensity upgrade. We have already developed and successfully operated a re-circulating He-gas stripper for 10-MeV/u uranium beams as an alternative to carbon foils. Recently, the 2nd gas stripper with air dedicated for 50-MeV/u ¹²⁴Xe beams was developed. The differential pumping techniques similar to that used in the He gas stripper was applied. We confined a very thick gas target, up to 20~mg/cm² of air, in a 0.5-m target chamber. One good feature of using air is that it can be inexhaustible for our use. The stripper was stably operated in user runs performed in June 2013. The service rate reached 91\%. The maximum beam intensity reached 38~pnA and the average intensity provided to users becomes approximately four times higher than it was in 2012. The down-time free gas strippers greatly contributed to these improvements. We also discuss the applicability of the air stripper to 50-MeV/u ²³⁸U beams.

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THPME195

Nondestructive Beam Current Monitor for the 88-inch Cyclotron

ion, ion-source, operation, heavy-ion

3738

M. Kireeff Covo
LBNL, Berkeley, California, USA

Funding: This work was supported by the Director, Office of Science, Office of Nuclear Physics, Division of Nuclear Physics, US Department of Energy under Contract No. DE-AC02-05CH11231.
A fast current transformer is mounted in the staging line of the Berkeley 88-inch isochronous cyclotron. The measured signal is amplified and connected to the input of a lock-in amplifier. The lock-in amplifier detects the signal vector from the input signal at the RF reference frequency of the cyclotron second harmonic. The magnitude of the signal detected is calibrated against a Faraday cup and shows the beam current leaving the cyclotron.

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THPRI083

Target Design for the ISODAR Neutrino Experiment

neutron, target, proton, shielding

3964

A. Bungau, R.J. Barlow
University of Huddersfield, Huddersfield, United Kingdom
J.R. Alonso, L.M. Bartoszek, J.M. Conrad, M. Moulai
MIT, Cambridge, Massachusetts, USA
M. Shaevitz
Columbia University, New York, USA

This paper focuses on the design of a high-intensity antineutrino source from the production and subsequent decay of Li8. The Geant4 code is used to calculate the anti-neutrino flux that can be obtained along with the production of undesirable contaminants. We present in this paper the optimised design for the target, moderators, reflector and shielding. Engineering issues associated with this design are also discussed in this paper.

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