Cyclotrons2019 - List of Keywords (HOM)

Paper	Title	Other Keywords	Page
TUB03	MRI-Guided-PT: Integrating an MRI in a Proton Therapy System	proton, GUI, FEM, simulation	144
	E. van der Kraaij, J. Smeets IBA, Louvain-la-Neuve, Belgium L. Bertora, A. Carrozzi, A. Serra ASG, Genova, Italy S. Gantz, A. Hoffmann, L. Karsch, A. Lühr, J. Pawelke, S. Schellhammer OncoRay, Dresden, Germany B. Oborn CMRP, Wollongong, Australia
	Integration of magnetic resonance imaging (MRI) in proton therapy (PT) has the potential to improve tumor-targeting precision. However, it is technically challenging to integrate an MRI scanner at the beam isocenter of a PT system due to space constraints and electromagnetic interactions between the two systems. We assessed the technical risks and challenges, and present a concept for the mechanical integration of a 0.5T MRI scanner (ASG MR-Open) into a PT gantry (IBA ProteusONE). Finite element simulations assess the perturbation of the gantry’s elements on the homogeneity of the scanner’s static magnetic field. MC simulations estimate the effect of the scanner’s magnetic field on the proton dose deposition. To test the technical feasibility, a first experimental setup was realized at the PT center in Dresden, combining a 0.22T open MRI scanner with a static proton beam line. Results show that the image quality is not degraded by proton beam irradiation if the acquisition is synchronized with beam line operation. The beam energy dependent proton beam deflection due to the scanner’s magnetic field is significant and needs to be corrected for in treatment planning and dose delivery.
	Slides TUB03 [1.866 MB]
DOI •	reference for this paper ※ https://doi.org/10.18429/JACoW-Cyclotrons2019-TUB03
About •	paper received ※ 14 September 2019 paper accepted ※ 26 September 2019 issue date ※ 20 June 2020
Export •	reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)

TUP020	Beam Properties at the Experimental Target Station of the Proton Therapy in Berlin	proton, radiation, experiment, scattering	199
	J. Bundesmann, A. Denker, J. Holz auf der Heide HZB, Berlin, Germany
	Beside the Therapy station for ocular tumors we have an experimental area to deliver protons and other ions. At this place there is also the possibility to do High Energy Pixe measurements on samples from cultural heritage. The positioning of the samples under test is possible by means of an xy-table with an range of 500x500 mm² and a load of at least 50 kg, reproducibility ±0.1 mm. We can change the beam size between 1 mm diameter as focused beam and up to 50 mm diameter with different scattering foils and homogeneous dose spread. We can deliver beam intensities from single protons up to 10¹² protons/cm² * sec The energy can be set to 68 MeV with a single Bragg peak, spread out Bragg peaks with a mechanical range shifter or absorber plates to reduce the energy. The timing properties range from quasi DC to a single pulse width of 1 ns with a repetition rate up to 2.4 MHz. Instead of a scattering foil to increase the beam spots we also can use beam scanning with the focused beam to reduce the beam losses. We will show the different beam properties at the experimental target area for radiation hardness testing of solar cells, optical elements and electronics under test.
DOI •	reference for this paper ※ https://doi.org/10.18429/JACoW-Cyclotrons2019-TUP020
About •	paper received ※ 14 September 2019 paper accepted ※ 25 September 2019 issue date ※ 20 June 2020
Export •	reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)

Paper

Title

Other Keywords

Page

TUB03

MRI-Guided-PT: Integrating an MRI in a Proton Therapy System

proton, GUI, FEM, simulation

144

E. van der Kraaij, J. Smeets
IBA, Louvain-la-Neuve, Belgium
L. Bertora, A. Carrozzi, A. Serra
ASG, Genova, Italy
S. Gantz, A. Hoffmann, L. Karsch, A. Lühr, J. Pawelke, S. Schellhammer
OncoRay, Dresden, Germany
B. Oborn
CMRP, Wollongong, Australia

Integration of magnetic resonance imaging (MRI) in proton therapy (PT) has the potential to improve tumor-targeting precision. However, it is technically challenging to integrate an MRI scanner at the beam isocenter of a PT system due to space constraints and electromagnetic interactions between the two systems. We assessed the technical risks and challenges, and present a concept for the mechanical integration of a 0.5T MRI scanner (ASG MR-Open) into a PT gantry (IBA ProteusONE). Finite element simulations assess the perturbation of the gantry’s elements on the homogeneity of the scanner’s static magnetic field. MC simulations estimate the effect of the scanner’s magnetic field on the proton dose deposition. To test the technical feasibility, a first experimental setup was realized at the PT center in Dresden, combining a 0.22T open MRI scanner with a static proton beam line. Results show that the image quality is not degraded by proton beam irradiation if the acquisition is synchronized with beam line operation. The beam energy dependent proton beam deflection due to the scanner’s magnetic field is significant and needs to be corrected for in treatment planning and dose delivery.

Slides TUB03 [1.866 MB]

DOI •

reference for this paper ※ https://doi.org/10.18429/JACoW-Cyclotrons2019-TUB03

About •

paper received ※ 14 September 2019 paper accepted ※ 26 September 2019 issue date ※ 20 June 2020

Export •

reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)

TUP020

Beam Properties at the Experimental Target Station of the Proton Therapy in Berlin

proton, radiation, experiment, scattering

199

J. Bundesmann, A. Denker, J. Holz auf der Heide
HZB, Berlin, Germany

Beside the Therapy station for ocular tumors we have an experimental area to deliver protons and other ions. At this place there is also the possibility to do High Energy Pixe measurements on samples from cultural heritage. The positioning of the samples under test is possible by means of an xy-table with an range of 500x500 mm² and a load of at least 50 kg, reproducibility ±0.1 mm. We can change the beam size between 1 mm diameter as focused beam and up to 50 mm diameter with different scattering foils and homogeneous dose spread. We can deliver beam intensities from single protons up to 10¹² protons/cm² * sec The energy can be set to 68 MeV with a single Bragg peak, spread out Bragg peaks with a mechanical range shifter or absorber plates to reduce the energy. The timing properties range from quasi DC to a single pulse width of 1 ns with a repetition rate up to 2.4 MHz. Instead of a scattering foil to increase the beam spots we also can use beam scanning with the focused beam to reduce the beam losses. We will show the different beam properties at the experimental target area for radiation hardness testing of solar cells, optical elements and electronics under test.

DOI •

reference for this paper ※ https://doi.org/10.18429/JACoW-Cyclotrons2019-TUP020

About •

paper received ※ 14 September 2019 paper accepted ※ 25 September 2019 issue date ※ 20 June 2020

Export •

reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)