Keyword: HOM
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WEBO01 Bench to Bedside: Translational Nuclear Medicine Research and Clinical Theranostics in PUMCH target, controls, data-analysis, ECR 179
 
  • L.H. Huo
    PUMCH, Beijing, People’s Republic of China
 
  PUMCH was founded In 1921. In 1958, PUMCH established the first nuclear medicine department in the country which eventually became the most comprehensive unit of nuclear medicine in China. The department has topped the ranking in "China’s Hospital Rankings" for consecutively 7 years and has done great efforts in translational research of nuclear medicine and molecular imaging. By now, over 10 isotopes and 100 radiopharmaceuticals are employed to support routine clinical work and more than 50 research projects as well, involving theranostic and preclinical exploration. These research achievements were highly glorified in the top international conferences and journals. The department not only keeps up with the advanced medical technologies in the world but also indulges in promoting novel technology applications in domestic hospitals. After a 60 years journey, the department of nuclear medicine in PUMCH with her superior capability will continuously lead nuclear medicine exploration and development in China. The department will begin another new and prosperous journey in the new era.  
slides icon Slides WEBO01 [17.823 MB]  
DOI • reference for this paper ※ doi:10.18429/JACoW-CYCLOTRONS2022-WEBO01  
About • Received ※ 22 May 2023 — Revised ※ 04 June 2023 — Accepted ※ 06 July 2023 — Issue date ※ 20 July 2023
Cite • reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)  
 
THPO010 An Automated Dose Verification Tool for Proton Therapy Plans Using Geant4/topas proton, FEM, framework, simulation 321
 
  • W. Wang, Y. Chen, P.L. Li, Y.C. Liao, X. Liu, B. Qin, Z.Y. Yang
    HUST, Wuhan, People’s Republic of China
 
  Funding: National Key Research and Development Program of China:2016YFC0105305, National Natural Science Foundation of China:12205111, Fundamental Research Funds for the Central Universities HUST:2022JYCXJJ010
Due to the PB algorithm’s limited accuracy, a higher accuracy dose verification tool is a legal requirement for proton therapy. Therefore, we developed an automated treatment plan dose verification framework based on the Monte-Carlo (MC) algorithm .The MC beam model was derived from commissioning data and fed into our automated software. CT and treatment plan from TPS were input for the automated software. The developed tool was validated and compared with the PB algorithm of Pinnacle3 TPS for 85 prostate patients. The difference between the PB dose and the MC dose of our automated tool was evaluated using gamma analysis (3 mm/3%, and 2mm/2% criteria) and mean absolute errors. Although the result shows good agreement and the passing rate was about 95%, the difference of all the indices was found to increase as the degree of tissue heterogeneity increased. The MC dose has a higher MAE in CTV, and femoral head compared to the PB dose. The automated software can facilitate patient plan verification in institutions and be useful for other clinical applications.
 
poster icon Poster THPO010 [0.719 MB]  
DOI • reference for this paper ※ doi:10.18429/JACoW-CYCLOTRONS2022-THPO010  
About • Received ※ 27 December 2022 — Revised ※ 13 February 2023 — Accepted ※ 17 February 2023 — Issue date ※ 17 July 2023
Cite • reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)