Author: Markov, N.V.
Paper Title Page
WECA02 Radiobiological Research with Charged Particles Beams in ITEP 128
 
  • N.V. Markov, A. Golubev, A.V. Kantsyrev, I. Roudskoy
    ITEP, Moscow, Russia
  • A. Golubev
    MEPhI, Moscow, Russia
  
  Radiobiological researches with heavy ions have been started at ITEP in 2006 on unique heavy ion accelerating facility ITEP-TWAC. The main purpose of these researches is study of the biological efficiency of carbon ions for different types of biological objects, such as tumor and normal cells, in the framework of the development of heavy ion therapy for cancer treatment in Russia. Another possible area of application of this research is the space radiobiology, studying stochastic and deterministic effects of ionizing radiation in the space environment on human. In this work the experimental setup for radiobiological research with heavy ions in ITEP, the dosimetry system for dose measurements and the results of the radiobiological researches with carbon ions are presented.  
slides icon Slides WECA02 [16.246 MB]  
 
WEPSB25 PRIOR Proton Microscope 214
 
  • D. Varentsov, P.M. Lang, M.E. Rodionova, L. Shestov, K. Weyrich
    GSI, Darmstadt, Germany
  • A.V. Bakhmutova, A.V. Bogdanov, A. Golubev, A.V. Kantsyrev, N.V. Markov, V.A. Panyushkin, A.I. Semennikov, V. Skachkov
    ITEP, Moscow, Russia
  • C.W. Barnes, F.G. Mariam, F.E. Merrill, C. Wilde
    LANL, Los Alamos, New Mexico, USA
  • S.V. Efimov, Y. Krasik, O. Oleg
    Technion, Haifa, Israel
  • A. Golubev
    MEPhI, Moscow, Russia
  • S. Udrea
    TU Darmstadt, Darmstadt, Germany
  • A.N. Zubareva
    IPCP, Chernogolovka, Moscow region, Russia
  
  Funding: Joint Helmholtz-ROSATOM FAIR-Russia Research Centre (HGF-IVF-IK-Ru-002)
The new proton radiography facility PRIOR* (Proton microscope for FAIR) was developed at SIS-18 accelerator at GSI (Darmstadt, Germany). PRIOR setup is designed for measurement, with high spatial resolution up to 10 mkm, of density distribution of static and dynamic objects by using a proton beam with energy up to 4.5 GeV. The magnetic system of the PRIOR beam-line consists of two sections. The first, matching section, contains electromagnetic-quadruple lenses and provides formation of a proton beam for the objects imaging task (beam size, angular distribution). The second section is a magnification (K ~4) section that consists of four Permanent Magnet Quadruples (PMQ) lenses. Tungsten collimators, installed at central plane of magnification section, provides regulation of contrast of the proton-radiographic images. Investigated object installed between first and second section. The registration system for static experiments consists of CsI scintillator and plastic scintillator (Bicron BC-412) for dynamic one with two types of intensified CCD cameras: PCO DiMAX and PCO DicamPro. In the first experiments with static objects with 3.6 Gev proton, was demonstrated a spatial resolution of 30 mkm. Dynamic commissioning was performed with target based on underwater electrical wires explosion with electrical pulse with current amplitude of ~200 kA and time duration of few microseconds.
* Merrill F.E. et al., Proton microscopy at FAIR, AIP Conf. Proc. 1195, 2009, p.667