Author: Yap, J.S.L.
Paper Title Page
MOPAB418 Tracking and LET Measurements with the MiniPIX-TimePIX Detector for 60 MeV Clinical Protons 1260
 
  • J.S.L. Yap, C.P. Welsch
    Cockcroft Institute, Warrington, Cheshire, United Kingdom
  • N.J.S. Bal
    NIKHEF, Amsterdam, The Netherlands
  • M.D. Brooke
    University of Oxford, Oxford, United Kingdom
  • C. Granja, C. Oancea
    ADVACAM s.r.o, Prague, Czech Republic
  • A. Kacperek
    The Douglas Cyclotron, The Clatterbridge Cancer Centre NHS Foundation Trust, Wirral, United Kingdom
  • C.P. Welsch, J.S.L. Yap
    The University of Liverpool, Liverpool, United Kingdom
  
  Funding: EU FP7 grant agreement 215080, H2020 Marie Sklodowska-Curie grant agreement No 675265, OMA - Optimization of Medical Accelerators and the Cockcroft Institute core grant STGA00076-01.
Recent advancements in accelerator technology have led the rapid emergence of particle therapy facilities worldwide, affirming the need for enhanced characterisation methods of radiation fields and radiobiological effects. The Clatterbridge Cancer Centre, UK operates a 60 MeV proton beam to treat ocular cancers and facilitates studies into proton induced radiobiological responses. Accordingly, an indicator of radiation quality is the linear energy transfer (LET), a challenging physical quantity to measure. The MiniPIX-Timepix is a miniaturised, hybrid semiconductor pixel detector with a Timepix ASIC, enabling wide-range measurements of the deposited energy, position and direction of individual charged particles. High resolution spectrometric tracking and simultaneous energy measurements of single particles enable the beam profile, time, spatial dose mapping and LET (0.1 to >100 keV/µm) to be resolved. Measurements were performed to determine the LET spectra in silicon, at different positions along the Bragg Peak (BP). We discuss the experimental setup, preliminary results and applicability of the MiniPIX for clinical environments. 		 
DOI • reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2021-MOPAB418  
About • paper received ※ 18 May 2021       paper accepted ※ 23 July 2021       issue date ※ 25 August 2021  
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MOPAB417 Preliminary Study of a Large Energy Acceptance FFA Beam Delivery System for Particle Therapy 1256
 
  • J.S.L. Yap, E.R. Higgins, S.L. Sheehy
    The University of Melbourne, Melbourne, Victoria, Australia
  
  The availability and use of ion beams for radiotherapy has grown significantly, led by technological developments to exploit the dosimetric advantages offered by charged particles. The benefits of particle therapy (PT) are well identified however its utilisation is still limited by high facility costs and technological challenges. A possibility to address both of these can be considered by improvements to the beam delivery system (BDS). Existing beamlines and gantries transport beams with a momentum range of ±1% and consequently, adjustments in depth or beam energy require all the magnetic fields to be changed. The speed to switch energies is a limiting constraint of the BDS and a determinant of the overall treatment time. A novel concept using fixed field alternating gradient (FFA) optics enables a large energy acceptance (LEA) as beams of varying energies can traverse the beamline at multiple physical positions given the same magnetic field. This presents the potential to provide faster, higher quality treatments at lower costs, with the capability to deliver advanced PT techniques such as multi-ion therapy. We explore the applicability and benefits of a LEA BDS.  
DOI • reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2021-MOPAB417  
About • paper received ※ 18 May 2021       paper accepted ※ 27 July 2021       issue date ※ 15 August 2021  
Export • reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)