Applications of Accelerators, Tech Transfer, Industry
Applications 01: Medical Applications
Paper Title Page
MOOBN4
State of the Art in Medical and Industrial Linear-Accelerator Systems  
 
  • D.W. Whittum
    Varian Medical Systems, Oncology Systems, Palo Alto, USA
 
  The speaker will address the state of the art in medical and industrial microwave accelerators. The main focus will be the history and technology of medical linacs for radiotherapy. Electron and hadron accelerator configurations should be described and operational aspects of gantry-style linac systems should be illustrated with reference to the state of the art. Aspects of structure design, modeling, testing and reliability should be discussed.  
 
TUP124 Phase Contrast Imaging Using a Single Picosecond X-ray Pulse of the Inverse Compton Source at the BNL Accelerator Test Facility 1062
 
  • M. Carpinelli
    Università di Sassari and INFN, Sassari, Italy
  • P. Delogu, M. Endrizzi
    INFN-Pisa, Pisa, Italy
  • B. Golosio, P. Oliva
    INFN-Cagliari, Monserrato (Cagliari), Italy
  • I. Pogorelsky, V. Yakimenko
    BNL, Upton, Long Island, New York, USA
 
  Inverse Compton scattering (ICS) X-ray sources are of current interest due to their novel features that enable new methods in medical and biological imaging. As a compelling example of such a possibility, we present an experimental demonstration of single shot inline phase contrast imaging using the ICS source located at the BNL Accelerator Test Facility. The phase contrast effect is clearly observed in the images obtained. Further, its qualities are shown to be in agreement with the predictions of theoretical models through comparison of experimental and simulated images of a set of plastic wires of differing composition and size. We also display an example of application of the technique to single shot phase contrast imaging of a biological sample.  
 
THP009 Collimator Design of 15 MeV Linear Accelerator Based Thermal Neutron Source for Radiography 2154
 
  • B.J. Patil, V.N. Bhoraskar, S.D. Dhole
    University of Pune, Pune, India
  • S.T. Chavan, R. Krishnan, S.N. Pethe
    SAMEER, Mumbai, India
  • A.J. Patil
    DANA, Pune, India
 
  Neutron Radiography is a powerful non-destructive testing technique used for the analysis of objects which are widely used in security, medical, nuclear and industrial applications. Optimization of the thermal neutron radiography facility has been carried out using 15 MeV LINAC based neutron source. In this case, a neutron collimator has been designed along with g-n target, moderator, reflector and shielding. The g-n target has been optimized based on their photonuclear threshold. The moderating properties have been studied for few light elements to optimize best suitable moderator for radiography system. The major part of the design was to optimize the collimator for neutron beam which decides quality of the image given. To get best values of collimator parameters such as collimation ratio, gamma content, neuron flux, cadmium ratio, beam uniformity, etc. a FLUKA simulation was carried out. The collimator has been optimized with cadmium lining square cone to capture the scattered thermal neutrons and the collimation ratio to L/D=18. The neutron flux of the optimized facility obtained at the object plane is 1.0·10+5 n/(cm2-sec1) and neutron to gamma ratio is 1.0·10+5 n/(cm2-mR1).  
 
THP010 Optimization of Dual Scattering Foil for 6 to 20 MeV Electron Beam Radiotherapy 2157
 
  • B.J. Patil, V.N. Bhoraskar, S.D. Dhole
    University of Pune, Pune, India
  • S.T. Chavan, R. Krishnan, S.N. Pethe
    SAMEER, Mumbai, India
 
  From last 50 years, electron beam therapy has an important radiation therapy modality. The electron beam from the LINAC is of size ~ 2 mm, whereas the size required for actual treatment is usually larger than 2 X 2 cm2 up to 30 X 30 cm2 at the isocenter. In the present work, it is proposed to use dual scattering foil system for production of clinical electron beam. The foils for 6 to 20 MeV electrons were optimized using the Monte Carlo based FLUKA code. The material composition, thickness of primary foil, Gaussian width and thickness of secondary foil were optimized such that it should meet the design parameters such as Dose at iso-center, beam uniformity, admixture of bremsstrahlung, etc. A pencil beam of electrons passing through primary foil converted into Gaussian shape and falling at the centroid of secondary foil which experienced maximum scattering, whereas falling at the edge experienced the minimum scattering. This results into flat profile of electron at isocenter. In conclusion, the primary scattering foil has been optimized with high Z element (Ta) having uniform thickness, whereas the secondary foil has been optimized with low Z element (Al) having Gaussian shape.  
 
THP012 Development of Imaging Techniques for Medical Accelerators in the QUASAR Group 2160
 
  • C.P. Welsch, T. Cybulski
    Cockcroft Institute, Warrington, Cheshire, United Kingdom
  • R. Boll, S. Sellner, S. Tegami
    MPI-K, Heidelberg, Germany
  • M. Holzscheiter
    UNM, Albuquerque, New Mexico, USA
  • C.P. Welsch
    The University of Liverpool, Liverpool, United Kingdom
 
  Funding: Work supported by the EU under contract PIIF-GA-2009-234814, PITN-GA-2008-215080 and DFG under WE3565/5.
Ions offer an increased precision in radiotherapy due to their specific depth-dose properties. This precision can only be fully exploited if exact knowledge of the particle beam properties, as well as the exact range of the particles in the inhomogeneous target, is available. The QUASAR Group has addressed the key issues in a number of different ways: Using a monolithic active pixel sensor, designed for dead time-free operation, we have developed a beam monitoring system capable of monitoring pulsed and continuous beams at typical therapeutic energies and intensities in real time during patient treatment; using a non-intrusive detector system based on the VELO detector, we will measure variations in beam properties without intersecting the beam core altogether; using liquid ionization chambers, we aim at obtaining information on the biological quality of the beam; using a simple set-up based on a silicon pixel detector, developed for the ALICE experiment, we have demonstrated the feasibility of detecting the distal edge of the Bragg peak in antiproton beams by detecting the pions resulting from pbar-nucleon annihilations. This paper gives an overview of these studies.
 
 
THP016 Design of an Achromatic and Uncoupled Medical Gantry for Radiation Therapy 2163
 
  • N. Tsoupas, D. Kayran, V. Litvinenko, W.W. MacKay
    BNL, Upton, Long Island, New York, USA
 
  Funding: Work supported by Brookhaven Science Associates, LLC under Contract No. DE-AC02-98CH10886 with the U.S. Department of Energy.
We are presenting the layout and the optics of a beam line to be used as a medical gantry in radiation therapy. The optical properties of the gantry’s beam line are such as to make the beam line achromatic and uncoupled. These two properties make the beam spot size, which is delivered and focused by the gantry, on the tumor of the patient, independent of the angular orientation of the gantry. In this paper we present the layout of the magnetic elements of the gantry, and also present the theoretical basis for the optics design of such a gantry.
* N. Tsoupas et. al. “Uncoupled achromatic tilted S-bend” Presented at the 11th Biennial European Particle Accelerator Conference, Genoa, Italy, June 23-27,2008