Paper |
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TUP007 |
Operational Experience in the Treatment of Ocular Melanomas with a New Digital Low-level RF Control System |
162 |
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- T. Fanselow, J. Bundesmann, A. Denker, U. Hiller
HZB, Berlin, Germany
- J.K. Abraham, J.L. Conradie, W. Duckitt
iThemba LABS, Somerset West, South Africa
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Ocular melanomas have been treated for the last 20 years at the Helmholtz-Zentrum Berlin in collaboration with the Charité Universitätsmedizin Berlin. However, parts of the initial control system electronics date back to the 1970s, when the machine was installed. Facing a critical shortage of legacy and obsolete components and with the down-time due to failures in the electronics on the increase, a decision was made to install the digital low-level RF control system, developed by iThemba LABS, on our K=132 cyclotron. A short description of the installation and commissioning process, which occurred in April 2017, and the experiences of the first 2 years of operation with the new digital low-level RF control system is presented.
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DOI • |
reference for this paper
※ https://doi.org/10.18429/JACoW-Cyclotrons2019-TUP007
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About • |
paper received ※ 14 September 2019 paper accepted ※ 25 September 2019 issue date ※ 20 June 2020 |
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TUP021 |
Towards FLASH Proton Irradiation at HZB |
202 |
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- G. Kourkafas, J. Bundesmann, A. Denker, T. Fanselow, J. Röhrich
HZB, Berlin, Germany
- V.H. Ehrhardt, J. Gollrad, J. Heufelder, A. Weber
Charite, Berlin, Germany
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The HZB cyclotron has been providing protons for eye-tumor treatment for more than 20 years. While it has been very successful using conventional dose rates (15-20 Gy/min), recent studies indicate that rapid irradiation with very high dose rates (FLASH) might be equally efficient against tumors but less harmful to healthy tissues. The flexible operation schemes of the HZB cyclotron can provide beams with variable intensities and time structures, covering a wide unexplored regime within the FLASH requirements (>40 Gy/s in <500 ms). This paper presents the results of the first FLASH beam production at HZB towards the establishment of an in-vivo clinical irradiation in the future.
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Poster TUP021 [1.031 MB]
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DOI • |
reference for this paper
※ https://doi.org/10.18429/JACoW-Cyclotrons2019-TUP021
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About • |
paper received ※ 12 September 2019 paper accepted ※ 25 September 2019 issue date ※ 20 June 2020 |
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TUC02 |
Status of the HZB Cyclotron |
253 |
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- A. Denker, J. Bundesmann, T. Damerow, T. Fanselow, D. Hildebrand, U. Hiller, I. Kailouh, G. Kourkafas, S. Ozierenski, C. Rethfeldt, J. Röhrich, S. Seidel, C. Zimmer
HZB, Berlin, Germany
- D. Cordini, J. Heufelder, R. Stark, A. Weber
Charite, Berlin, Germany
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For more than 20 years eye tumours are treated in collaboration with the Charité - Universitätsmedizin Berlin. The close co-operation between Charité and HZB permits joint interdisciplinary research. Irradiations with either a sharp, well focused or a broad beam, either in vacuum or in air are possible. In addition, a 60Co-source for gamma-irradiations is available. Experiments now comprise dosimetry, detector comparisons, ambulant mouse irradiations, including class I gene-modified mice. Furthermore, radiation hardness tests on detectors, CCD-cameras and other electronics are performed. In order to improve the beam diagnosis between the 2 MV injector Tandetron and the cyclotron a harp has been installed, leading to new beam line calculations for the injection line. The accelerator operation for therapy as well as on-going experiments and results will be presented.
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Slides TUC02 [1.965 MB]
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DOI • |
reference for this paper
※ https://doi.org/10.18429/JACoW-Cyclotrons2019-TUC02
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About • |
paper received ※ 14 September 2019 paper accepted ※ 25 September 2019 issue date ※ 20 June 2020 |
|
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reference for this paper using
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※ LaTeX,
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