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@inproceedings{belikhin:rupac2021-mopsa45, author = {Belikhin, M.A. Belikhin and A.P. Chernyaev and A.A. Pryanichnikov and A.E. Shemyakov}, title = {{Experimental Simulation of Volume Repainting Technique at Proton Synchrotron in Context of Spot Scanning Proton Therapy}}, % booktitle = {Proc. RuPAC'21}, booktitle = {Proc. 27th Russ. Part. Accel. Conf. (RuPAC'21)}, eventdate = {2021-09-27/2021-10-01}, pages = {192--195}, eid = {MOPSA45}, language = {english}, keywords = {target, radiation, proton, HOM, simulation}, venue = {Alushta, Crimea}, series = {Russian Particle Accelerator Conference}, number = {27}, publisher = {JACoW Publishing}, location = {Geneva, Switzerland}, date = {2021-10}, month = {10}, year = {2021}, issn = {2673-5539}, isbn = {978-3-95450-240-0}, doi = {10.18429/JACoW-RuPAC2021-MOPSA45}, url = {https://jacow.org/rupac2021/papers/mopsa45.pdf}, abstract = {{Background: Reduction the influence of respiration-induced intrafractional motion of tissues is one of the main tasks of proton therapy with a scanning beam. Repainting is one of the techniques of motion compensation. It consists in multiple repeated irradiations of the entire volume or individual iso-energy layers with a dose that is a multiple of the prescribed dose. As a result, the dose is averaged, which leads to an increase in the uniformity of the dose field. Purpose: Experimental simulation of volume sequential repainting and dosimetric estimation of its capabilities in the context of spot scanning proton therapy (SSPT) using dynamic phantom. Materials and Methods: Simulation of respiration-like translational motion is performed using the non-anthropomorphic water dynamic phantom. Target of this phantom is compatible with EBT-3 films. Estimation of repainting technique is based on the analysis of average dose, dose uniformity in region of interests located within planning target volume, and dose gradients. Results: Repainting was estimated for motion with amplitudes of 2, 5, 10 mm with different number of iterations up to 10 at the prescribed dose of 6 Gy. This one increased the uniformity of the dose field from 85,9\% to 96,0\% at an amplitude of 10 mm and 10 iterations. Conclusions: Volume repainting improves the uniformity of dose distribution. However, the irradiation time increases, and the dose gradients deteriorate in proportion to the amplitude of motion.}}, }