RuPAC2016 - List of Authors (Fadeev, A.M.)

Paper	Title	Page
WEPSB049	Temperature Control System for Thermoradiotherapy Facilities	474
	S.M. Polozov, A.M. Fadeev, S.M. Ivanov MEPhI, Moscow, Russia E.A. Perelstein JINR, Dubna, Moscow Region, Russia
	It is known, hyperthermia is widely used to improve the efficiency of cancer treatment. Local hyperthermia is a method where only tumor is heated, on the other hand healthy tissues are protected from overheating. It was proposed to use an array of eight independently phased dipoles operating on 100-150 MHz to focus the RF energy in deep-situated volume of 30-50 mm size. But the problem of non-invasive temperature measurement should to be solved for correct operation of the local thermoradiotherapy systems. Conventional invasive thermometry devices as thermocouples, thermistors or Bragg optical sensors can not be widely used because of serious risk of the cancer cells transport to healthy tissues. Radiothermometry or acoustic thermometry can not be used for tissues located deeper than 5-7 cm. As known electrodynamics characteristics of tissues depend on temperature. It was proposed to use this effect for active radiothermometry in local hyperthermia. Two opposite RF dipoles can be used as generator and receiver of pick-up signal. It was shown by simulations that such method can be used for thermometry of deep-situated tissues and have high resolution. Results of simulation will present in report.
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WEPSB050	Laboratory Model of Thermoradiotherapy Facility: Experimental Results	477
	S.M. Polozov, A.M. Fadeev, S.M. Ivanov MEPhI, Moscow, Russia E.A. Perelstein JINR, Dubna, Moscow Region, Russia
	Hyperthermia combined with radiotherapy (thermoradiotherapy) or with chemotherapy is one of promising approach to improve the cancer treatment efficiency. The treatment of deep-situated tumors is a problem which can not be solved by means of traditional facilities developed for whole-body or regional hyperthermia because of overheating of healthy tissues and blood. A cylindrical array of independently phased dipoles was proposed to focus electromagnetic energy in deep-situated tumors. It was early shown by simulations that array of eight independently phased dipoles operating on 100-150 MHz can be used to focus energy in an ellipsoid of 30-50 mm in size. Later the laboratory model of thermoradiotherapy facility was developed and constructed and series of experiments were carried out. Results of experiments and its comparison with simulations will discuss in report.
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Paper

Title

Page

Temperature Control System for Thermoradiotherapy Facilities

474

S.M. Polozov, A.M. Fadeev, S.M. Ivanov
MEPhI, Moscow, Russia
E.A. Perelstein
JINR, Dubna, Moscow Region, Russia

It is known, hyperthermia is widely used to improve the efficiency of cancer treatment. Local hyperthermia is a method where only tumor is heated, on the other hand healthy tissues are protected from overheating. It was proposed to use an array of eight independently phased dipoles operating on 100-150 MHz to focus the RF energy in deep-situated volume of 30-50 mm size. But the problem of non-invasive temperature measurement should to be solved for correct operation of the local thermoradiotherapy systems. Conventional invasive thermometry devices as thermocouples, thermistors or Bragg optical sensors can not be widely used because of serious risk of the cancer cells transport to healthy tissues. Radiothermometry or acoustic thermometry can not be used for tissues located deeper than 5-7 cm. As known electrodynamics characteristics of tissues depend on temperature. It was proposed to use this effect for active radiothermometry in local hyperthermia. Two opposite RF dipoles can be used as generator and receiver of pick-up signal. It was shown by simulations that such method can be used for thermometry of deep-situated tissues and have high resolution. Results of simulation will present in report.

Export •

reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)

WEPSB050

Laboratory Model of Thermoradiotherapy Facility: Experimental Results

477

S.M. Polozov, A.M. Fadeev, S.M. Ivanov
MEPhI, Moscow, Russia
E.A. Perelstein
JINR, Dubna, Moscow Region, Russia

Hyperthermia combined with radiotherapy (thermoradiotherapy) or with chemotherapy is one of promising approach to improve the cancer treatment efficiency. The treatment of deep-situated tumors is a problem which can not be solved by means of traditional facilities developed for whole-body or regional hyperthermia because of overheating of healthy tissues and blood. A cylindrical array of independently phased dipoles was proposed to focus electromagnetic energy in deep-situated tumors. It was early shown by simulations that array of eight independently phased dipoles operating on 100-150 MHz can be used to focus energy in an ellipsoid of 30-50 mm in size. Later the laboratory model of thermoradiotherapy facility was developed and constructed and series of experiments were carried out. Results of experiments and its comparison with simulations will discuss in report.

Export •

reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)