Author: Das, M.K.
Paper Title Page
THPD36 An Embedded System Based Computer Controlled Process Automation for Recovery and Purification of 99mTc from (n, γ)99Mo 211
 
  • A. De, P. Bhaskar, A. Dutta Roy, M. Garai, V.K. Khare, S. Kumari, S.S. Pal, S. Saha, S.K. Thakur
    VECC, Kolkata, India
  • L. Barua, S. Chattopadhyay, M.K. Das, U. Kumar, S. Saha Das
    BRIT, Bidhan Nagar, India
 
  99Mo produced 99mTc (t1/2=6hr, 140keV γ-ray) is the most useful radioisotope for nuclear diagnostics. High specific activity 99Mo is supplied globally mainly by five old reactors whose routine or unscheduled maintenance shutdown causes supply irregularities that adversely affects patient management in nuclear medicine centres. 99mTc may also be produced via 98Mo(n,γ) in a natural MoO3 target in reactor or by 100Mo(n,2n)99Mo or 100Mo(p,2n)99mTc reaction in cyclotron. To meet the crisis proposals are there to produce 99Mo by 100Mo(n,2n)99Mo or 99mTc directly by 100Mo(p,2n)99mTc in a cyclotron. Of the several separation methods of 99mTc from molybdenum, the most common are adsorption column chromatography, sublimation and liquid-liquid solvent extraction. The conventional methods besides being cumbersome are often hazardous, polluting, require skilled manpower and facilities like fume hood and so are not always practically feasible for hospitals. To address these, VECC and BRIT, Kolkata have collaborated to develop an embedded system based automated 99Mo/99mTc generator from low specific activity 99Mo using solvent extraction technique, supervised by a PC based GUI.  
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