NAPAC2016 - List of Authors (Garson, A.B.)

Paper	Title	Page
TUPOA27	From Relativistic Electrons to X-ray Phase Contrast Imaging	341
	A.H. Lumpkin Fermilab, Batavia, Illinois, USA M.A. Anastasio, A.B. Garson Washington University in St. Louis, St. Louis, Missouri, USA
	Funding: Work at Fermilab partly supported by Fermi Research Alliance, LLC under Contract No.DE-AC02-07CH11359 with the U.S.DoE. Work at Washington Univ. in St. Louis was supported in part by NSF CBET1263988. X-ray phase contrast (XPC) imaging is an emerging technology that holds great promise for biomedical applications due to its ability to provide information about soft tissue structure . The need for high spatial resolution at the boundaries of the tissues is noted for this process. Based on results from imaging of relativistic electron beams with single crystals , we proposed transferring single-crystal imaging technology to this bio-imaging issue. Using a microfocus x-ray tube (17 kVp) and the exchangeable phosphor feature of the camera system, we compared the point spread function (PSF) of the system with the reference P43 phosphor to that with several rare earth garnet single crystals of varying thickness. Based on single Gaussian peak fits to the collimated x-ray images, we observed a four times smaller system PSF (21 microns (FWHM)) with the 25-mm diameter single crystals than with the reference polycrystalline phosphor's 80-micron value. Initial images of 33-micron diameter carbon fibers have also been obtained with small crystals installed. Tests with a full-scale 88-mm diameter single crystal (patent-pending configuration) are being planned. A. Appel, M.A. Anastasio, and E.M. Brey, Tissue Eng. Part B Rev 17 (5), 321 (2011). **A.H. Lumpkin, et al., Phys. Rev. ST-AB 14 (6), 060704 (2011).
DOI •	reference for this paper ※ https://doi.org/10.18429/JACoW-NAPAC2016-TUPOA27
Export •	reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)

Paper

Title

Page

From Relativistic Electrons to X-ray Phase Contrast Imaging

341

A.H. Lumpkin
Fermilab, Batavia, Illinois, USA
M.A. Anastasio, A.B. Garson
Washington University in St. Louis, St. Louis, Missouri, USA

Funding: Work at Fermilab partly supported by Fermi Research Alliance, LLC under Contract No.DE-AC02-07CH11359 with the U.S.DoE. Work at Washington Univ. in St. Louis was supported in part by NSF CBET1263988.
X-ray phase contrast (XPC) imaging is an emerging technology that holds great promise for biomedical applications due to its ability to provide information about soft tissue structure *. The need for high spatial resolution at the boundaries of the tissues is noted for this process. Based on results from imaging of relativistic electron beams with single crystals **, we proposed transferring single-crystal imaging technology to this bio-imaging issue. Using a microfocus x-ray tube (17 kVp) and the exchangeable phosphor feature of the camera system, we compared the point spread function (PSF) of the system with the reference P43 phosphor to that with several rare earth garnet single crystals of varying thickness. Based on single Gaussian peak fits to the collimated x-ray images, we observed a four times smaller system PSF (21 microns (FWHM)) with the 25-mm diameter single crystals than with the reference polycrystalline phosphor's 80-micron value. Initial images of 33-micron diameter carbon fibers have also been obtained with small crystals installed. Tests with a full-scale 88-mm diameter single crystal (patent-pending configuration) are being planned.
*A. Appel, M.A. Anastasio, and E.M. Brey, Tissue Eng. Part B Rev 17 (5), 321 (2011).
**A.H. Lumpkin, et al., Phys. Rev. ST-AB 14 (6), 060704 (2011).

DOI •

reference for this paper ※ https://doi.org/10.18429/JACoW-NAPAC2016-TUPOA27

Export •

reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)