DAFNE, the Frascati F-factory the collider where the Crab-Waist collision scheme has been implemented and successfully tested, is presently working for a physics program in the field of exotic atoms. The present scientific program foresees the study and the characterization of the never observed before kaonic deuterium. Providing a suitable data sample for such measurement requires the collider to provide the highest flux of k- meson and the lowest possible background shower on the detector. The operation strategy, and the collider setup in terms of collisions and beam dynamics are presented and discussed.