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URLhttps://doi.org/10.18429/JACoW-IPAC2023-THPM058
TitleConceptual design of a compact synchrotron-based facility for cancer therapy and biomedical research with helium and proton beams
Authors
  • M. Vretenar, G. Tranquille, J. Borburgh, K. Palskis, L. Bottura, M. Angoletta, T. Torims
    European Organization for Nuclear Research
  • D. Adliene
    Lithuanian Association of Medical Physicists and Engineers
  • E. Benedetto
    South East European International Institute for Sustainable Technologies
  • M. Sapinski
    Paul Scherrer Institut
  • R. Taylor
    CERN
  • e. Gershkevitsh
    Estonian Society for Biomedical Engineering and Medical Physics
  • e. korobeinikova
    Lithuanian Society for Radiation Therapy
  • m. kalnina
    Latvian Association of Radiologists
AbstractThanks to their superior dose conformality and higher radiobiological effectiveness with respect to protons, helium ions are considered as the new tool of choice in the fight against cancer using particle beams. A facility to produce helium beams at therapeutical energy can also accelerate protons, at energies permitting both standardised treatment and full body radiography, and heavier ions for treatment of shallow tumours and for research. Equipped with FLASH extraction, it will be able to couple the protection to healthy tissues provided by Bragg peak and FLASH effect. This paper will present the basic layout of a facility based on a compact synchrotron of new design that can accommodate a wide research programme with patient treatment, sharing the beam between two treatment rooms and an experimental room. The linac accelerator may be designed to allow a programme for production of new radioisotopes for therapy, diagnostics and theragnostics using helium ions, in parallel with the operation as synchrotron injector. Overall cancer and conventional radiotherapy statistics, along with an estimate on the number of patients that can benefit from this facility will be presented for the case of the Baltic States, a candidate for hosting the facility.
Paperdownload: THPM058.pdf
CiteBibTeX, LaTeX, Text/Word, RIS, EndNote
Conference14th International Particle Accelerator Conference
Series
LocationVenice, Italy
Date07-12 May 2023
PublisherJACoW Publishing, Geneva, Switzerland
Editorial BoardRalph Assmann - Deutsches Elektronen-Synchrotron DESY Peter McIntosh - Science and Technology Facilities Council (STFC/DL/ASTeC) Giovanni Bisoffi - Istituto Nazionale di Fisica Nucleare (INFN/LNL) Alessandro Fabris - Elettra-Sincrotrone Trieste S.C.p.A. Ivan Andrian - Elettra-Sincrotrone Trieste S.C.p.A. Giulia Vinicola - Istituto Nazionale di Fisica Nucleare (INFN/LNF)
Online ISBN978-3-95450-231-8
Online ISSN2673-5490
Received03 May 2023
Revised08 May 2023
Accepted19 June 2023
Issued26 September 2023
DOI10.18429/JACoW-IPAC2023-THPM058
Pages5024-5027