JACoW is a publisher in Geneva, Switzerland that publishes the proceedings of accelerator conferences held around the world by an international collaboration of editors.
@inproceedings{reindl:ibic2023-mop002,
author = {J. Reindl and J. Bundesmann and G. Datzmann and A. Denker and A. Dittwald and G. Dollinger and G. Kourkafas and J. Neubauer and A. Rousseti},
% author = {J. Reindl and J. Bundesmann and G. Datzmann and A. Denker and A. Dittwald and G. Dollinger and others},
% author = {J. Reindl and others},
title = {{MiniBEE - Minibeam Beamline for Preclinical Experiments}},
% booktitle = {Proc. IBIC'23},
booktitle = {Proc. 12th Int. Beam Instrum. Conf. (IBIC'23)},
eventdate = {2023-09-10/2023-09-14},
pages = {34--36},
paper = {MOP002},
language = {english},
keywords = {proton, radiation, target, cyclotron, simulation},
venue = {Saskatoon, Canada},
series = {International Beam Instrumentation Conference},
number = {12},
publisher = {JACoW Publishing, Geneva, Switzerland},
month = {12},
year = {2023},
issn = {2673-5350},
isbn = {978-3-95450-236-3},
doi = {10.18429/JACoW-IBIC2023-MOP002},
url = {https://jacow.org/ibic2023/papers/mop002.pdf},
abstract = {{Spatial fractionated radiotherapy using protons, so-called proton minibeam radiotherapy (pMBT) was developed for better sparing of normal tissue in the entrance channel of radiation. Progressing towards clinical use, pMBT should overcome current technical and biomedical limitations. This work discusses a preclinical pMBT facility, currently built at the 68.5MeV cyclotron at the Helmholtz Zentrum Berlin. The goal is to irradiate small animals using focused pMBT with a σ of 50µm, a high peak-to-valley dose ratio at center-to-center distance as small as 1mm and beam current of 1nA. A first degrader defines the maximum energy of the beam. Dipole magnets and quadrupole triplets transport the beam to the treatment room while multiple slits properly form the transverse beam profiles. A high magnetic field gradient triplet lens forms the minibeams in front of the target station and, scanning magnets are used for a raster scan at the target. An additional degrader, positioned close before the focusing spot and the target, further reduces the energy, forming a spread-out Bragg peak. A small animal radiation research platform will be used for imaging and positioning of the target.}},
}