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MOP15 | The ISOLPHARM Project for the Production of High Specific Activity Radionuclides for Medical Applications | 91 |
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ISOLPHARM is a branch of the INFN-LNL SPES project*, aimed at the production of radioisotopes for medical applications according to the ISOL technique. Such an innovative method will allow to obtain radiopharmaceuticals with very high specific activity. In this context a primary proton beam, extracted from a cyclotron will directly impinge a target, where the produced isotopes are extracted and accelerated, and finally, after mass separation, only the desired nuclei are deposed on a secondary target. This work is focused in the design and study of the aforementioned production targets for a selected set of isotopes, in particular for 64Cu, 89Sr, 90Y, 125I and 131I. 64Cu will be produced impinging Ni targets, otherwise the SPES UCx target is planned to be used. Different target configurations are being studied by means of the Monte Carlo based code FLUKA for the isotope production calculation and the Finite Element Method based software ANSYS ® for the temperature level evaluation. An appropriate secondary target substrate for implanting the produced isotopes is under study alongside with a system for its dissolution and repartition into radiopharmaceutical doses.
* A. Monetti et al., The RIB production target for the SPES project, Eur. Phys. J. A (2015) 51:128 |
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THA02 | New Developments at iThemba LABS | 274 |
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iThemba LABS has been in operation for more than 30 years and is now at a stage at which refurbishment and ' in some cases ' replacement of the infrastructure and critical components is required. The replacement and refurbish-ment of the cooling system, which include the cooling tow-ers and chillers, the 4.4-MVA uninterruptable power sup-ply batteries and other critical components, are discussed. Progress with a facility for low-energy radioactive ion beams will be reported on. A proposal to remove radioiso-tope production from the separated sector cyclotron (SSC) and the production of the future radioisotopes with a com-mercial 70-MeV cyclotron to make more beam time avail-able for nuclear physics research with the SSC will also be discussed. Developments on our electron cyclotron reso-nance ion sources, the PIG ion source and low-level digital RF control system have also been carried out. Good pro-gress with integration of the existing control system to an EPICS control system has been made. The adoption of EtherCAT as our new industrial communication standard has enabled integration with much off-the-shelf motion, actuator and general interface hardware. | ||
Slides THA02 [4.138 MB] | ||
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