IPAC2018 - List of Authors (Poortmans, P.)

Paper	Title	Page
MOPML051	First Performance Calculations for the Very High Energy Electron Radiation Therapy Experiment at PRAE	516
	A. Faus-Golfe LAL, Orsay, France R. Delorme, Y. Prezado IMNC, Orsay, France V. Favaudon, C. Fouillade, S. Heinrich, A. Mazal, A. Patriarca, P. Poortmans, P. Verrelle Institut Curie - Centre de Protonthérapie d'Orsay, Orsay, France A. Hrybok National Taras Shevchenko University of Kyiv, Radiophysical Faculty, Kiev, Ukraine
	The Platform for Research and Applications with Electrons (PRAE) project aims at creating a multidisciplinary R&D platform at the Orsay campus, joining various scientific communities involved in radiobiology, subatomic physics, instrumentation, particle accelerators and clinical research around a high-performance electron accelerator with beam energies up to 70 MeV and later 140 MeV, in order to perform a series of unique measurements and challenging R&D. In this paper we will report the first optics design and performance evaluations of such a multidisciplinary machine, focusing on Very High Energy Electrons (VHEE) innovative Radiation Therapy (RT) applications in particular by allowing Grid and FLASH methodologies, which are likely to represent a major breakthrough in RT. Functional specifications include beam intensities to produce dose rates from 2 Gy/min to 100Gy/sec, beam sizes with diameters from 0.5 mm to 10 cm or more of homogeneous beams and monitoring devices with accuracy in the order of 1-2% for single or multiple beams and single or multiple fractions in biological and ppreclinical applications. High energies (>140 MeV) would be also needed for GRID therapy.
DOI •	reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2018-MOPML051
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Paper

Title

Page

First Performance Calculations for the Very High Energy Electron Radiation Therapy Experiment at PRAE

516

A. Faus-Golfe
LAL, Orsay, France
R. Delorme, Y. Prezado
IMNC, Orsay, France
V. Favaudon, C. Fouillade, S. Heinrich, A. Mazal, A. Patriarca, P. Poortmans, P. Verrelle
Institut Curie - Centre de Protonthérapie d'Orsay, Orsay, France
A. Hrybok
National Taras Shevchenko University of Kyiv, Radiophysical Faculty, Kiev, Ukraine

The Platform for Research and Applications with Electrons (PRAE) project aims at creating a multidisciplinary R&D platform at the Orsay campus, joining various scientific communities involved in radiobiology, subatomic physics, instrumentation, particle accelerators and clinical research around a high-performance electron accelerator with beam energies up to 70 MeV and later 140 MeV, in order to perform a series of unique measurements and challenging R&D. In this paper we will report the first optics design and performance evaluations of such a multidisciplinary machine, focusing on Very High Energy Electrons (VHEE) innovative Radiation Therapy (RT) applications in particular by allowing Grid and FLASH methodologies, which are likely to represent a major breakthrough in RT. Functional specifications include beam intensities to produce dose rates from 2 Gy/min to 100Gy/sec, beam sizes with diameters from 0.5 mm to 10 cm or more of homogeneous beams and monitoring devices with accuracy in the order of 1-2% for single or multiple beams and single or multiple fractions in biological and ppreclinical applications. High energies (>140 MeV) would be also needed for GRID therapy.

DOI •

reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2018-MOPML051

Export •

reference for this paper using ※ BibTeX, ※ LaTeX, ※ Text/Word, ※ RIS, ※ EndNote (xml)